Re: [ccp4bb] Sugar-Pi-stacking

2017-08-23 Thread Bärbel Blaum
B@JISCMAIL.AC.UK] on behalf of Bernhard Rupp [hofkristall...@gmail.com] Sent: Wednesday, August 23, 2017 8:18 PM To: CCP4BB@JISCMAIL.AC.UK <mailto:CCP4BB@JISCMAIL.AC.UK> Subject: [ccp4bb] Sugar-Pi-stacking Hi Fellows, there are some smart chemists amongst you, so I wonder - what precisely

Re: [ccp4bb] Sugar-Pi-stacking

2017-08-23 Thread Bernhard Rupp
4BB@JISCMAIL.AC.UK> Subject: [ccp4bb] Sugar-Pi-stacking Hi Fellows, there are some smart chemists amongst you, so I wonder - what precisely am I to understand is the nature of pi-stacking between an aromatic residue or (whatever pi-orbital moiety) and a sugar moiety, disaccharide etc.?

Re: [ccp4bb] Sugar-Pi-stacking

2017-08-23 Thread Boaz Shaanan
K] on behalf of Bernhard Rupp [hofkristall...@gmail.com] Sent: Wednesday, August 23, 2017 8:18 PM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] Sugar-Pi-stacking Hi Fellows,   there are some smart chemists amongst you, so I wonder – what precisely am I to understand is the nature of pi-stacking be

Re: [ccp4bb] Sugar-Pi-stacking

2017-08-23 Thread Christian Roth
Dear Bernhard, the explanation can be found in here with additional references in. J Am Chem Soc. 2015 Dec 9;137(48):15152-60. doi: 10.1021/jacs.5b08424. Epub 2015 Nov 30. Carbohydrate-Aromatic Interactions in Proteins. Hope tha

Re: [ccp4bb] Sugar-Pi-stacking

2017-08-23 Thread Ian Tickle
Hi Bernhard Greetings! I don't see how an aromatic-aliphatic interaction can be classed as pi-stacking. Surely it's just a normal dispersion interaction ( https://en.wikipedia.org/wiki/London_dispersion_force)? Cheers -- Ian On 23 August 2017 at 18:18, Bernhard Rupp wrote: > Hi Fellows, >

[ccp4bb] Sugar-Pi-stacking

2017-08-23 Thread Bernhard Rupp
Hi Fellows, there are some smart chemists amongst you, so I wonder - what precisely am I to understand is the nature of pi-stacking between an aromatic residue or (whatever pi-orbital moiety) and a sugar moiety, disaccharide etc.? Thanks for your help, BR -