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- Original Message -
From: Miriam-Rose Ash <[EMAIL PROTECTED]>
Date: Friday, October 5, 2007 8:46 am
Subject: [ccp4bb] Domain swapping..... and unswapping.
To: CCP4BB@JISCMAIL.AC.UK
> Hey all,
>
> So
Dear Miriam
I had that case of the 4-helix bundle FAT domain of Focal Adhesion
Kinase. It crystallised as a helix-swapped dimer (PDB ID 1k04,
1mol/ASU), as a non-swapped 4helix bundle (1ow7, 3 mol/ASU), and as a
hybrid, where 2 mols / ASU were not swapped, and one was swapped (1ow6).
With be
@JISCMAIL.AC.UK
Subject: [ccp4bb] Domain swapping. and unswapping.
Hey all,
Sorry for the off-topic post, but I'm just wondering if anyone has heard
of any examples in which a single crystal contained both the
domain-swapped and unswapped forms of a protein?
Thanks!
Miriam
Disclaimer
This communic
We've had a case recently (unpublished) with 4 molecules in the
asymmetric unit, two self-contained and two domain-swapped
(asymmetrically)
... anything is possible, though in this case the "domains" are
really separate proteins expressed as an artificial fusion
Phil
On 5 Oct 2007, at 1
Hey all,
Sorry for the off-topic post, but I'm just wondering if anyone has heard of any
examples in which a single crystal contained both the domain-swapped and
unswapped forms of a protein?
Thanks!
Miriam
