Hi Pat,
The CCP4 suite, particularly ccp4sm, was tested on M1/2 + macOS 15.
We ordered an M4 laptop several weeks ago and will soon be able to test it in
M4 + macOS 15.
Currently, the solution is to install CCP4 using a tar.gz file available from
the CCP4 download page. Optional packages can be
Yes, I agree this is a good point. We had an example at a CCP-EM workshop where
the participant’s map turned out to have the wrong hand. I’m embarrassed to say
that it took Tristan Croll (sitting next to me) to notice that the helices were
left-handed! Anyway, flipping the hand was quick and eas
Hello Johan and Natesh,
There is more info about the terminology in this article:
https://doi.org/10.1038/s41586-024-07215-4
In brief, yes, "Coulomb potential map" or "electrostatic potential map" is most
correct (as far as I remember). But "cryoEM map" is widely accepted as a
shortcut, and is
Hello Matthew,
This is a very good point. With good maps one can tell if it’s the correct hand
by visually inspecting the alpha-helices (or from features of the quaternary
structure for some complexes), but sometimes it is more difficult. I don’t know
how em_placement and emplace_local behave w
Hi all
Slice'N'Dice is another option for this. It will take a structure eg an AF2
prediction, remove low-confidence portions, and split the remainder using a
variety of algorithms, including based on the PAE where that is available.
Originally developed for MR
(https://www.biorxiv.org/conten
