[ccp4bb] CBMS Structural Biology Workbench September 27 to 29 - Registration open

Dear Colleagues, We'd like to bring to your attention that the registration is open for the CBMS Structural Biology Workbench, scheduled September 27 through 29. Participants can choose between SAXS and MX or attend both. The event will be held virtually. Registration is free: https://www.bnl

[ccp4bb] Launch of IUCrData Raw Data Letters: Editorial

Dear Colleagues, I imagine you will be interested to know of the launch of IUCrData’s Raw Data Letters. The Main Editor is Dr Loes Kroon Batenburg. See https://forums.iucr.org/viewtopic.php?f=39&t=449&p=729#p729 Greetings, John Emeritus Professor John R Helliwell DSc Chair of IUCr CommDat ##

Re: [ccp4bb] ISO model with large groups of atoms in alternative conformations

Crambin (quick search for “Martha Teeter” and “Crambin” should yield dividends)? There are some very high resolution structures of that with multiple conformations. Harry > On 23 Aug 2022, at 23:02, Pavel Afonine wrote: > > Dear community, > > I’m looking for an example of a crystal structu

Re: [ccp4bb] ISO model with large groups of atoms in alternative conformations

Hi Pavel, I guess one which might a very good example for your requirements is Urease from sporosarcina pasteurii. The active side is covered by a “mobile flap” (chain C, residues 320- 340). Depending on the active site bound molecule (substrate analogue, inhibitor, …) the flap can occur in th

Re: [ccp4bb] ISO model with large groups of atoms in alternative conformations

Dear Pavel, Recently we determined the structure of a fusion protein with 2.5 chains in the AU in P3(2)21 (I posted this case in the ccp4bb). The protein forms a pentamer with one chain sitting on the 2-fold. I refined it in P3(2) with 4 well defined chains and the 5th chain having two confor

Re: [ccp4bb] ISO model with large groups of atoms in alternative conformations

Dear Pavel, One of my colleagues solved this structure ( https://www.rcsb.org/structure/2gn0). I watched in awe while he built and explained the structure. Hopefully the structure is useful -Bharath On Tue, Aug 23, 2022 at 6:03 PM Pavel Afonine wrote: > Dear community, > > > > I’m looking for a

Re: [ccp4bb] ISO model with large groups of atoms in alternative conformations

Dear Pavel, I have seen this in very high-resolution models of triclinic lysozyme but I don't remember the PDB ids. Best wishes, Kay On Tue, 23 Aug 2022 15:02:07 -0700, Pavel Afonine wrote: >Dear community, > > > >I’m looking for an example of a crystal structure where a large group of >atoms