Re: [ccp4bb] [6HR5] collected on an Eiger so Rmerge not relevant

First of all, you are of course correct, Rmerge (as Rmeas, Rpim, CC1/2, I/sigma ...) is not detector-dependent. Second, when looking at the "experiment" section of the PDB deposition, I note that some Rmerge values are even given there! The statistics there are dubious, e.g. seemingly the I/si

Re: [ccp4bb] [EXTERNAL] [ccp4bb] [6HR5] collected on an Eiger so Rmerge not relevant

Hi Clemens, I fully agree with you, especially on overall data collection strategy and on image deposition. It looks like an interesting and mysterious case. Mean I Over Sigma is reported as 2.2 - I'm curious why resolution was not extend. Since they disregarded Rmerge (a reasonable thing to

Re: [ccp4bb] [EXTERNAL] [ccp4bb] [6HR5] collected on an Eiger so Rmerge not relevant

Hi, On Wed, Jul 31, 2019 at 07:11:10PM +0100, Weston Lane wrote: > Thanks for the response. I did look at the multiplicity of the > datasets in their table and while I suppose 6.9x redundancy is sort > of high for P2 spacegroup it's actually lower than some of the other > datasets (presumably non-

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Re: [ccp4bb] [EXTERNAL] [ccp4bb] [6HR5] collected on an Eiger so Rmerge not relevant

Edward, Thanks for the response. I did look at the multiplicity of the datasets in their table and while I suppose 6.9x redundancy is sort of high for P2 spacegroup it's actually lower than some of the other datasets (presumably non-Eiger) in the table with good overall Rmerge (e.g. a C2 datase

Re: [ccp4bb] [EXTERNAL] [ccp4bb] [6HR5] collected on an Eiger so Rmerge not relevant

I think it is not really the detector, but the strategy. If you decrease exposure time by a factor of ten and make up for it by 10 x higher redundancy, then obviously R-merge, which is a measure of accuracy of the individual frames, is going to suffer. Chi^2 statistics can distinguish this from

[ccp4bb] [6HR5] collected on an Eiger so Rmerge not relevant

I was looking at the following structure in the PDB: http://www.rcsb.org/structure/6HR5 I noticed that the R/Rfree stats were pretty high for 2.9A resolution so I followed up by looking for the "Table 1" statistics in the journal article. Link to article: https://www.nature.com/articles/s41

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