First of all, you are of course correct, Rmerge (as Rmeas, Rpim, CC1/2, I/sigma ...) is not detector-dependent.
Second, when looking at the "experiment" section of the PDB deposition, I note that some Rmerge values are even given there! The statistics there are dubious, e.g. seemingly the I/sigma in the high resolution shell is 2.2 meaning that they could have used higher resolution data. Third, look at the sliders on the entry page: the validity of this PDB entry is suspicious - quite bad Rfree and geometry. One more case for the deposition of raw data. In my eyes, the RCSB policy should be that raw data must be deposited when accepting such a bad entry. HTH, Kay On Wed, 31 Jul 2019 17:49:47 +0100, Weston Lane <wesl...@gmail.com> wrote: >I was looking at the following structure in the PDB: >http://www.rcsb.org/structure/6HR5 I noticed that the R/Rfree stats were >pretty high for 2.9A resolution so I followed up by looking for the "Table 1" >statistics in the journal article. Link to article: >https://www.nature.com/articles/s41589-019-0311-9 Table is located in the >supplemental materials "Table 9". > >From the processing statistics it's clear that the diffraction from that >crystal wasn't great but I don't want to get hung up on the processing or the >validity of the structure. What struck me what this little explanation the >authors included to explain the outlier statistics in the table: > >"Crystal of P36_S1_25 was collected on an Eiger detector, so Rmerge data are >not relevant." > >We all know that Rmerge isn't a great metric for data quality but I've never >heard that it's detector-dependent. This doesn't make sense to me. If it's >actually true can someone explain, please? > >Thanks! > >Wes > >######################################################################## > >To unsubscribe from the CCP4BB list, click the following link: >https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
