[ccp4bb] Imperial College London - Postdoctoral Research Fellow position - X-ray crystallography

2018-08-16 Thread Cota Segura, Ernesto
Postdoctoral Research Fellow position at Imperial College London We are seeking an outstanding structural biologist to contribute to an ongoing drug discovery project in the groups of Dr Ernesto Cota (Department of Life Sciences) and Prof Edward Tate (Department of Chemistry), funded by Cancer

Re: [ccp4bb] How to fix residual B value problem in pdbredo

2018-08-16 Thread Robbie Joosten
Hi Kahkashan, Thanks for your faith in pdb-redo. I'm glad you are happy with the results. If you download the zip file with all output, there is a file called _final_tot.pdb this one has the total B-factors as ANISOU records. Cheers, Robbie On 16 Aug 2018 18:11, Firdous Tarique wrote: He

[ccp4bb] How to fix residual B value problem in pdbredo

2018-08-16 Thread Firdous Tarique
*Hello everyoneI have a structure whose quality improves a lot when submitting it to PDB-Redo server. But when I am trying to put the output coordinates for validation it is not taking up and comes with message that: Structure contains Residual B values and TLS records are present but required ANIS

[ccp4bb] Coot: Failed to load module

2018-08-16 Thread nic steussy
All, I am having difficulty running Coot through my ccp4 install since I upgraded to Ubuntu 18.04 (MATE variant).  The error:  steussy@osprey:~$ coot Gtk-Message: Failed to load module "gail" Gtk-Message: Failed to load module "atk-bridge" Gtk-Message: Failed to load module "gail" Gtk-Message:

[ccp4bb] Post-doc and PhD student positions available in Poznan

2018-08-16 Thread Mirek Gilski
Dear All, I'd like to draw your attention to the openings for Post-doc at Center for Biocrystallographic Research (Poznan, Poland), to work on a combination of protein crystallography and supramolecular chemistry. The project overview can be found at: http://www.man.poznan.pl/CBB/JOBS/POF.pdf

[ccp4bb] Senior Research Investigator at Bristol-Myers Squibb in X-ray crystallography and cryo-EM

2018-08-16 Thread Sheriff, Steven
All: Bristol-Myers Squibb has an open Ph.D. level position in X-ray crystallography and cryo-EM. The only way to apply for this position is through the following web site: * https://bristolmyerssquibb.wd5.myworkdayjobs.com/BMS/job/Princeton---NJ---US/Senior-Research-Investigator_R15084

Re: [ccp4bb] crystals that dont diffract :( :(

2018-08-16 Thread Patrick Shaw Stewart
Hi Careina Expanding on what Tim says, try crushing your crystals to make a seed stock, and adding it to a few *random screens - *preferably screens that you have already tried with this target. Search for instructions for MMS or rMMS online. Good luck, Patrick On 14 August 2018 at 11:34, Ti

Re: [ccp4bb] Fishing crystals from volatile solvent as precipitant

2018-08-16 Thread Patrick Shaw Stewart
Hi Thomas One problem with conventional approaches is that you tend to get high mosaicity when harvesting from drops with isopropanol. A very good method, invented by my old friend Lesley Haire, that has always worked (so far!) is to use microbatch-under-oil with a plate called the Vapor Batch pl