Hi Steven,
In a word, lots :) In somewhat more detail
If this is a request to the CCP4 community, then the images and crystallization
metadata from the Hauptman-Woodward Medical Research Institute High-Throughput
Crystallization Center are packed in a rar format and users of the Center
Yes, the pH optimum of a reaction can be changed with a mutation of one
of the catalytic residue or with a neighboring non-catalytic residue. A
classic example is the K166R mutation of mandelate racemase.
see: Biochemistry. 1995 Mar 7;34(9):2788-97
https://www.ncbi.nlm.nih.gov/pubme
Does the Hauptman-Woodward Medical Research Institute have any sample
data-sets, so we can see what the results look like?
On 4/14/2017 8:58 AM, Edward Snell wrote:
Dear Elizabeth,
The High-Throughput Crystallization Screening Center and the
Hauptman-Woodward Medical Research Institute
Yes - convincing..
Follow Jacob's advice and see how the maps look.
Eleanor
On 15 April 2017 at 06:04, Alex Lee wrote:
> Thanks Eleanor,
> If I understand right, there is just 1 TFZ. TFZ== means "Translation
> Function Z-score equivalent, only calculated for the top solution after
> refinement (
