Does the Hauptman-Woodward Medical Research Institute have any sample
data-sets, so we can see what the results look like?
On 4/14/2017 8:58 AM, Edward Snell wrote:
Dear Elizabeth,
The High-Throughput Crystallization Screening Center and the
Hauptman-Woodward Medical Research Institute has been operating for
over a decade with considerable success. There are comprehensive
details at http://getacrystal.org but basically your samples are
screened against a large range of commercially available conditions
plus some more unique ones. Video microscope images are provided over
a period of six weeks or longer by request and the imaging also
includes SONICC (detecting very tiny crystals or crystals in
precipitate) and UV-TPEF to ensure the sample is protein. There are a
large range of analysis tools that can be used on the data. Much of
the information is provided on the link above. Success rates are
pretty high and many entries in the PDB have had their initial crystal
hits there.
I hope this helps, the center does not advertise much but works with a
lot of laboratories.
Cheers,
Eddie.
Edward Snell Ph.D.
President and CEO Hauptman-Woodward Medical Research Institute
Assistant Prof. Department of Structural Biology, University at Buffalo
700 Ellicott Street, Buffalo, NY 14203-1102
hwi.buffalo.edu <http://hwi.buffalo.edu/>
Phone: (716) 898 8631 Fax: (716) 898 8660
Skype: eddie.snell Email: esn...@hwi.buffalo.edu
<mailto:esn...@hwi.buffalo.edu>
Heisenberg was probably here!
------------------------------------------------------------------------
*From:* CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of
Elizabeth Diaz <lizlaurendia...@gmail.com>
*Sent:* Friday, April 14, 2017 9:06 AM
*To:* CCP4BB@JISCMAIL.AC.UK
*Subject:* [ccp4bb] Recommendations for Robotic Crystal Screening
Services
All,
I am currently attempting to crystallize a peptide/protein complex and
am wanting to know about robotic screening services that you would
recommend. We have done some in house conditions with little luck, and
want to broaden our search, but that would require going externally
for screening. Do you have any recommendations for robotic crystal
screening services, preferably in the United States?
Thank you so much,
Elizabeth Diaz
University of Delaware
