Hello Carlos
thanks for your kindly reply. I think the cif file ( GLC_mon_lib.cif ) is only
for one glucose molecule, it can not regulate the bond between two glucose
units, that is why they break apart in the real space refinement.
in the pdb file , different glucoses are different molecu
Hello,
I am looking for the latest and complete list of marketed drugs that
were developed using Structure Based approach. Could someone please help
me in finding this information or provide me the references.
Thanks
Sridhar
Dear Users,
Through the Collaborative Crystallography Pilot Program (CC) at the
Advanced Light Source, scientists can send protein crystals to Berkeley
Center for Structural biology (BCSB) staff researchers for data
collection and analysis. The CC Pilot Program can provide an number of
benef
hello everyone
can anyone help me with sugar ( say maltoheptaose) refinement in coot?
I use the pdb file with " GLC " name , it always breaks apart into
discountinuous glucose when I try to use real space refinement , I believe that
is because there is no restraint with regarding to bond , w
Dear Users,
Through the Collaborative Crystallography Pilot Program (CC) at the
Advanced Light Source, scientists can send protein crystals to
Berkeley Center for Structural biology (BCSB) staff researchers for data
collection and analysis. The CC Pilot Program can provide
a number of benefit
Hi Everyone,
Could someone please tell me how to display the evolutionary/
phylogenetic tree of the homologs of my protein of interest.
When I perform a PSI-BLAST search for my protein, I receive about 130
top hits for homologs. The NCBI or EBI tools that I've laid my hands
on seem to only
Dear all,
Thank you for the suggestions regarding cartoon problem that I posted on
bulletin board. The problem was due to the separate segID put out after the
phenix refinement. According to the PDB format, if I am not wrong, column
number 73 should be blank which is followed by element name. But
Thanks a lot for all the helpful replies I got!
Here is a summary:
- increase drop size to 4+4ul if protein is not the limiting factor ->
limits skin formation
- add 10-20ul well solution directly to drop
- freeze straight from the drop
- microseeding into less conc. AmSO4 to get more crystals
Dear all,
thanks a lot for the many replies suggesting me what to put in my
"misterious" density.
Molecules that have been suggested are: acetate, Mg ion with waters,
bicarbonate or nitrate, sulphate, borate, glycerol, tris, alternative
conformation of the Arg side chain, waters.
I have to say tha
