Mario
You guys don't be so modests. Implement the "idea" could take me
quite some time and you
guys does it so easy (at least for me point of view :-) and nice. And is
a good oportunity for me to Thanks for your many ideas...
Regards
Mario
Gerard DVD Kleywegt wrote:
Quite a beauty.
Dear Miriam,
We have seen this in our study of the FOXP2/DNA complexes (Stroud et al.,
Structure, 14, 159-16, 2006).
Lin
Lin Chen, Ph.D.
Associate Professor
Molecular and Computational Biology
University of Southern California
1050 Childs Way, Los Angeles, CA 90089
Phone: 213-821-4277
Fax: 213
Dear Miriam
I had that case of the 4-helix bundle FAT domain of Focal Adhesion
Kinase. It crystallised as a helix-swapped dimer (PDB ID 1k04,
1mol/ASU), as a non-swapped 4helix bundle (1ow7, 3 mol/ASU), and as a
hybrid, where 2 mols / ASU were not swapped, and one was swapped (1ow6).
With be
Dear CCP4 Users,
We have an opening for one federally funded post-doctoral position for a
structural biologist or protein biochemist to study bacterial voltage-gated
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Hi Miriam,
If you check PDB ID 1K50 you would see that the
asymmetric unit contains two monomers and a domain swapped dimmer. The
reference if you want to read the paper is:
O`Neill, J.W., Kim, D.E., Johnsen, K., Baker, D., Zhang,
K.Y. Single-site mutations induce 3D d
We've had a case recently (unpublished) with 4 molecules in the
asymmetric unit, two self-contained and two domain-swapped
(asymmetrically)
... anything is possible, though in this case the "domains" are
really separate proteins expressed as an artificial fusion
Phil
On 5 Oct 2007, at 1
Hey all,
Sorry for the off-topic post, but I'm just wondering if anyone has heard of any
examples in which a single crystal contained both the domain-swapped and
unswapped forms of a protein?
Thanks!
Miriam
=
SYNCHROTRON BEAM TIME FOR MACROMOLECULAR CRYSTALLOGRAPHY
AT THE UNDULATOR BEAMLINE X06SA AT SLS FROM JANUARY-APRIL 2008
=
- PILATUS 6M pixel detector available for u
Warren,
Quite a beauty... what a nice way to show the effect of the
mutation in the binding site.
really nice,
Mario
Warren DeLano wrote:
http://delsci.com/morph
It's a start...
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