Hi Michael,
Sure, I'll try to dig into it and construct a patch that adds this feature.
I stumbled upon this after converting data between the 'VCF' and
'VRanges' class. The primary use case I had in mind is having a more
efficient storing and processing for short InDels, or defining variants
This was a consideration. I guess I've never got much use out of them being
DNAStringSets, so I just went with the simple character vectors. It makes
sense to support DNAStringSet. I could imagine someone e.g. wanting to
represent mutations at the protein-level, and structural variants will
require
Hi,
Would it be reasonable to (optionally) allow storing the reference and
alternative alleles in the 'VRanges' class as a 'DNAStringSet'?
Currently, 'character' and 'Rle' are possible. Having a 'DNAStringSet'
would make it more consistent with the rest of the 'VariantAnnotation'
framework a
