Hi,
Would it be reasonable to (optionally) allow storing the reference and
alternative alleles in the 'VRanges' class as a 'DNAStringSet'?
Currently, 'character' and 'Rle' are possible. Having a 'DNAStringSet'
would make it more consistent with the rest of the 'VariantAnnotation'
framework and make use of the efficient 'Biostrings' string handling
infrastructure.
Best wishes
Julian
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