Re: [ccp4bb] Postdoc positions at MRC-LMB & CCPEM/STFC

[Burnley, Tom (STFC,RAL,SC)]

Dear all,

A gentle reminder that the deadlines for applications are due this week... 
Friday 23 October for the STFC/CCP-EM position and Sunday 25 October for the 
MRC-LMB position.

Best wishes,

Tom and Sjors


From: CCP4 bulletin board  on behalf of Burnley, Tom 
(STFC,RAL,SC) 
Sent: 25 September 2020 13:21
To: ccp4bb 
Subject: [ccp4bb] Postdoc positions at MRC-LMB & CCPEM/STFC

Dear all,

For those interesting in computational cryoEM development...

We are excited to announce two new PDRA positions in the Scheres’ group 
(MRC-LMB, UK) and the CCP-EM group (STFC RAL, UK).  These two positions will 
work closely together as part of a wider project with the Alan Turing Institute 
and the Department of Applied Mathematics and Theoretical Physics at Cambridge 
University to investigate molecular structure from images under physical 
constraints.

In brief, the LMB position will focus on developing and implementing new 
machine-learning-driven algorithms within the RELION framework.  The STFC 
position will focus on the data capture and training for these algorithms (as 
well as for the wider community), alongside application to molecular modelling. 
 For full details and application please see:

LMB position:

https://mrc.tal.net/vx/lang-en-GB/mobile-0/appcentre-1/brand-3/xf-15f5592f8769/candidate/so/pm/4/pl/1/opp/1377-Postdoctoral-Scientist-Structural-Studies-Dr-Sjors-Scheres-LMB-1377/en-GB

STFC position:

https://www.topcareer.jobs/Vacancy/irc255076_10934.aspx

For those interested in both positions, we encourage you to apply for both. If 
you are unsure or would like further information please contact us.

Best wishes,

Tom and Sjors

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[ccp4bb] Postdoctoral positions: SARS-CoV-2 cryo-EM Columbia University

[Lawrence Shapiro]

Two Postdoctoral Scientist positions: Cryo-EM of neutralizing antibodies 
targeting SARS-CoV-2 
Shapiro Lab
Columbia University in New York City

We have positions available in two related research programs: 
First, structure/function work with SARS CoV-2-neutralizing antibodies, 
conducted in collaboration with Prof. David Ho of the Aaron Diamond AIDS 
Research Center (ADARC) at Columbia (see eg our recent paper in Nature on 
identification of potent neutralizing antibodies from convalescent patients 
treated at Columbia, https://www.nature.com/articles/s41586-020-2571-7). This 
project is funded by the NIH and the Jack Ma Foundation.
Second, in collaboration with Prof. Richard Friesner of Columbia Chemistry and 
also founder of Schrodinger, Inc., we will determine high-resolution structures 
(for example of SARS-CoV-2 spike complexes with neutralizing antibodies), and 
use these structures for advanced computational methods to optimize therapeutic 
properties. This project is funded by the Bill and Melinda Gates Foundation.
Our lab is equipped with state-of the-art instrumentation for protein 
production and biochemistry, Cryo-EM, and x-ray crystallography. With respect 
to Cryo-EM, in our own building we have access to an FEI Titan Krios microscope 
with a K3 direct-electron detector. Four additional Krios microscopes are 
available elsewhere on the Columbia campus, and six additional Krios 
microscopes at the nearby New York Structural Biology Center. Our lab is part 
of the vibrant Columbia and NYC structural biology communities, providing 
numerous opportunities for interaction with experts on multiple topics. 

Candidates should have a PhD in Structural Biology/Biophysics or related 
disciplines, and a track record of research achievements. Knowledge of protein 
purification and experience in structural biology are essential. Protein 
crystallographers with map interpretation and model building experience are 
encouraged to apply.

Competitive salary, comprehensive benefits, and assistance with housing are 
provided.
Inquiries should be made to Prof. Lawrence Shapiro (l...@columbia.edu).





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