Let us look at a piece of the relevant code from "logistf" package:
iter <- iter + 1 XW2 <- crossprod(x, diag(pi * (1 - pi))^0.5) Fisher <- crossprod(t(XW2)) covs <- solve(Fisher) H <- crossprod(XW2, covs) %*% XW2 if (firth) U.star <- crossprod(x, y - pi + diag(H) * (0.5 - pi)) else U.star <- crossprod(x, y - pi) delta <- as.vector(covs %*% U.star) mx <- max(abs(delta))/maxstep if (mx > 1) delta <- delta/mx First, note that this is inside an iterative loop. The Fisher information matrix is first formed, and then it is inverted to get `covs'. This is where it can get troublesome. It is very likely in your case that the `Fisher' information matrix is ill-conditioned, and hence `covs' cannot be computed. Consequently, the steplength `delta' for the Newton method cannot be determined. Ravi. ____________________________________________________________________ Ravi Varadhan, Ph.D. Assistant Professor, Division of Geriatric Medicine and Gerontology School of Medicine Johns Hopkins University Ph. (410) 502-2619 email: rvarad...@jhmi.edu ----- Original Message ----- From: xiaoyan yu <xiaoyan...@gmail.com> Date: Tuesday, March 9, 2010 11:26 am Subject: [R] penalized maximum likelihood estimation and logistf To: r-help@r-project.org > Hi, I got two questions and would really appreciate any help from here. > First, is the penalized maximum likelihood estimation(Firth Type Estimation) > only fit for binary response (0,1 or TRUE, FALSE)? Can it be applied > to > multinomial logistic regression? > If yes, what's the formula for LL and U(beta_i)? Can someone point > me to > the right reference? > Second, when I used *logistf *on a dataset with binary response, I > got the > following error msg: > "Error in if (mx > 1) delta <- delta/mx : > missing value where TRUE/FALSE needed" > > What does this msg mean? does it mean the dataset includes missing response? > I checked my dataset several times and didn't find anything other > than TRUE > or FALSE for the response. Please shed light on this. > > Thanks, > Xiaoyan > > [[alternative HTML version deleted]] > > ______________________________________________ > R-help@r-project.org mailing list > > PLEASE do read the posting guide > and provide commented, minimal, self-contained, reproducible code. ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.