Dear Hsin-Ya,

The problem here is that subject is a factor with 14 levels, and sequence again is a factor with 2 levels; so the subject:sequence interaction already uses up another (13*1)=13 d.f.; given that there are only 28 replicates, it is not surprising that there are no residual degrees of freedom left!

What do you intend to test with your model? Maybe I can be of help to solve the 
problem

Best wishes
Christoph



[EMAIL PROTECTED] schrieb:
Dear Dr. Christoph:

Thanks for your reply.  I am sure that I use the same data to run GLM with 
SPSS, but SPSS seems work!!
I also try your suggestion. I change the sequence data. a<-c(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14)
b<-c(1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2)
c<-c(2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2)
d<-c(2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1)
d<-c(1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1)
e<-c(1739,1633,1481,1837,1780,2073,1374,1629,1555,1385,1756,1522,1566,1643,1939,
     1615,1475,1759,1388,1483,1127,1682,1542,1247,1235,1605,1598,1718 )
KK<-data.frame(subject=as.factor(a), drug=as.factor(b), period=as.factor(c), 
sequence=as.factor(d), Max=e)
lm3<- lm(Max ~ subject*sequence + period + drug+sequence , data=KK)
print(lm3)
anova(lm3)

However, it can not work!!
So, where is the problems?  Do I misunderstand what you mean?


Best regards,
Hsin-Ya


Dr. Christoph Scherber wrote:
Dear Hsin-Ya Lee,

The problem seems to be that every subject always only received one
sequence:

      sequence
subject 1 2
      1  0 2
      2  2 0
      3  0 2
      4  2 0
      5  0 2
      6  2 0
      7  0 2
      8  2 0
      9  0 2
      10 2 0
      11 0 2
      12 2 0
      13 0 2
      14 2 0


You should try to use a design where each subject receives each of the two
sequences. Otherwise obviously the interactions will be not available.

Best wishes
Christoph




leeznar schrieb:
Dear R-users:

I am a new R-user and I have a question about lm
function.  Here is my data.
a<-c(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14)
b<-c(1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2,1,2)
c<-c(2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2)
d<-c(2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1,2,2,1,1)
e<-c(1739,1633,1481,1837,1780,2073,1374,1629,1555,1385,1756,1522,1566,1643,1939,1615,1475,1759,1388,1483,1127,1682,1542,1247,1235,1605,1598,1718
)
Data<-data.frame(subject=as.factor(a),
drug=as.factor(b), period=as.factor(c),
sequence=as.factor(d), Max=e)

lm3<- lm(Max ~subject*sequence + sequence + period +
drug, data=Data)
print(lm3)
anova(lm3)

When I use lm to fit the data, there are some problems
in "subject*sequence".   I have use GLM in SPSS to
fit the same data, and it seems there is no problem.
I don't know where my problem is.  How can I get the
same result with SPSS? How can I do?

Best regards,
Hsin-Ya Lee




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