Hi David,
your function works just fine if I take nly the region into account. But
unfortunately it does not consider the first column of the chromosomes.
There can be an overlap between the two tables only if the regions are on
the same chromosome. This is why the first column of both tables is a
prerequisite for the analysis.
I treid somehow to create a second argument to consider this, but until now
without success.
If you have any Ideas I will be grateful.
Thanks
Assa
(I send it only to r-help, as iti si besically an R-question and not
specific to bioconductor, but I still think it is also something to do with
bioc as it deals with chromosome regions. But anyway, I think you were right
about it.)
On Tue, Oct 25, 2011 at 18:01, David Winsemius <dwinsem...@comcast.net>wrote:
>
> On Oct 25, 2011, at 10:40 AM, Assa Yeroslaviz wrote:
>
> Hi all,
>>
>> @Martin - thanks for the help it works very good.
>>
>> @David - sorry for the misunderstanding. I will see to it, that it won't
>> happen again.
>> BTW, unfortunately your function is not working.
>> It is patialy my error as I gave no regions with overlaps, but even after
>> changing them it just doesn't fit.
>>
>> Here is the new data with an overlap in the third gene:
>>
>> genetable <- rd.txt("name chr start end str
>> accession Length
>>
>> gen1 4 646752 646838 + MI0005806 86
>> gen12 2L 243035 243141 - MI0005821 106
>> gen3 2L 159838 159928 + MI0005813 90
>> gen7 2L 1831685 1831799 - MI0011290 114
>> gen4 2L 2737568 2737661 + MI0017696 93")
>> loctable <- rd.txt("Chr Start End length
>>
>> 4 136532 138654 2122
>> 3 139870 141970 2100
>> 2L 157838 160440 2602
>> X 160834 162966 2132
>> 4 204040 208536 4496")
>>
>> But I still get:
>>
>>> apply(genetable, 1, function(x) inregion(x, loctable[, c("Start",
>>>
>> "End")]) )
>> [1] FALSE FALSE FALSE FALSE FALSE
>>
>
> You just want to pass the start and end columns of genetable
>
>
> > # Helper function
> > inregion <- function(vec, locs) {
> + any( apply(locs, 1, function(x) vec["start"]>x[1] &
> vec["end"]<=x[2])) }
> > # Test the function
> > inregion(genetable[2, ], loctable[, c("Start", "End")])
> [1] FALSE
> > # [1] FALSE
> >
> > apply(genetable[, 3:4], 1, function(x) inregion(x, loctable[, c("Start",
> "End")]) )
> [1] FALSE FALSE TRUE FALSE FALSE
>
> ( I really wish that you would stop crossposting. I am only following your
> bad practice because you posted my code on BioC.)
>
> --
> David
>
>>
>> for the single queries I get TRUE:
>>
>> inregion(genetable[3, ], loctable[, c("Start", "End")])
>>>
>> [1] TRUE
>>
>> Do you have Idea, as to how I can fix this problem?
>>
>> Thanks and again sorry for the trouble.
>>
>> Assa
>>
>> On Tue, Oct 25, 2011 at 15:48, Martin Morgan <mtmor...@fhcrc.org> wrote:
>>
>> On 10/25/2011 03:42 AM, Assa Yeroslaviz wrote:
>>>
>>> Hi everybody,
>>>>
>>>> I would like to know whether it is possible to compare to tables for
>>>> certain
>>>> parameters.
>>>> I have these two tables:
>>>> gene table
>>>> name chr start end str accession Length
>>>> gen1 4 646752 646838 + MI0005806 86
>>>> gen12 2L 243035 243141 - MI0005821 106
>>>> gen3 2L 159838 159928 + MI0005813 90
>>>> gen7 2L 1831685 1831799 - MI0011290 114
>>>> gen4 2L 2737568 2737661 + MI0017696 93
>>>> ...
>>>>
>>>> localization table:
>>>> Chr Start End length
>>>> 4 136532 138654 2122
>>>> 3 139870 141970 2100
>>>> 2L 157838 158440 602
>>>> X 160834 162966 2132
>>>> 4 204040 208536 4496
>>>> ...
>>>>
>>>> I would like to check whether a specific gene lie within a certain
>>>> region.
>>>> For example I want to see if gene 3 on chromosome 2L lies within the
>>>> region
>>>> given in the second table.
>>>>
>>>>
>>> Hi Assa --
>>>
>>> In Bioconductor, use the GenomicRanges package. Create two GRanges
>>> objects
>>>
>>> genes = with(genetable, GRanges(chr, IRanges(start, end), str,
>>> accession=accession, Length=length)
>>> locations = with(locationtable, GRanges(Chr, IRanges(Start, End)))
>>>
>>> then
>>>
>>> olaps = findOverlaps(genes, locations)
>>>
>>> queryHits(olaps) and subjectHits(olaps) index each gene with all
>>> locations
>>> it overlaps. The definition of 'overlap' is flexible, see ?findOverlaps.
>>>
>>> Martin
>>>
>>>
>>>
>>> What I would like to is like
>>>> 1. check if the gene lies on a specific chromosome
>>>> 1.a if no - go to the next line
>>>> 1.b if yes - go to 2
>>>> 2. check if the start position of the gene is bigger than the start
>>>> position
>>>> of the localization table AND if it smaller than the end position (if it
>>>> lies between the start and end positions in the localization table)
>>>> 2.a if no - go to the next gene
>>>> 2.b if yes - give it to me.
>>>>
>>>> I was having difficulties doing it without running into three
>>>> interleaved
>>>> conditional loops (if).
>>>>
>>>> I would appreciate any help.
>>>>
>>>> Thanks
>>>>
>>>> Assa
>>>>
>>>> [[alternative HTML version deleted]]
>>>>
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>>>> >
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>>>> >
>>>>
>>>>
>>>
>>> --
>>> Computational Biology
>>> Fred Hutchinson Cancer Research Center
>>> 1100 Fairview Ave. N. PO Box 19024 Seattle, WA 98109
>>>
>>> Location: M1-B861
>>> Telephone: 206 667-2793
>>>
>>>
>> [[alternative HTML version deleted]]
>>
>> ______________________________**________________
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>> PLEASE do read the posting guide http://www.R-project.org/**
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>>
>
> David Winsemius, MD
> West Hartford, CT
>
>
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