I thought I would have another try at explaining my problem. I think that last time I may have buried it in irrelevant detail.
This output should explain my dilemma: > dim(S) [1] 1455 269 > summary(as.vector(S)) Min. 1st Qu. Median Mean 3rd Qu. Max. -1.160e+04 0.000e+00 0.000e+00 -4.132e-08 0.000e+00 8.636e+03 > sum(as.vector(S)==0)/(1455*269) [1] 0.8451794 # S is a large moderately sparse matrix with some large elements > SS <- crossprod(S,S) > (eigen(SS,only.values = TRUE)$values)[250:269] [1] 9.264883e+04 5.819672e+04 5.695073e+04 1.948626e+04 1.500891e+04 [6] 1.177034e+04 9.696327e+03 8.037049e+03 7.134058e+03 1.316449e-07 [11] 9.077244e-08 6.417276e-08 5.046411e-08 1.998775e-08 -1.268081e-09 [16] -3.140881e-08 -4.478184e-08 -5.370730e-08 -8.507492e-08 -9.496699e-08 # S'S fails to be non-negative definite. I can't show you how to produce S easily but below I attempt at a reproducible version of the problem: > set.seed(091207) > X <- runif(1455*269,-1e4,1e4) > p <- rbinom(1455*269,1,0.845) > Y <- p*X > dim(Y) <- c(1455,269) > YY <- crossprod(Y,Y) > (eigen(YY,only.values = TRUE)$values)[250:269] [1] 17951634238 17928076223 17725528630 17647734206 17218470634 16947982383 [7] 16728385887 16569501198 16498812174 16211312750 16127786747 16006841514 [13] 15641955527 15472400630 15433931889 15083894866 14794357643 14586969350 [19] 14297854542 13986819627 # No sign of negative eigenvalues; phenomenon must be due # to special structure of S. # S is a matrix of empirical parameter scores at an approximate # mle for a model with 269 paramters fitted to 1455 observations. # Thus, for example, its column sums are approximately zero: > summary(apply(S,2,sum)) Min. 1st Qu. Median Mean 3rd Qu. Max. -1.148e-03 -2.227e-04 -7.496e-06 -6.011e-05 7.967e-05 8.254e-04 I'm starting to think that it may not be a good idea to attempt to compute large information matrices and their determinants! Murray Jorgensen ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.