Well PyPy is just an implementation of Python among many others (but limited to
version 2.7). It is not a web server. If you want to make PyPy interact with a
web server (such as nginx) you have to use a special protocol such as WSGI or
Fast-CGI. For best performances you can for instance use uWSGI that integrates
well with nginx but for this you have to recompile nginx. As you see it's a bit
complex, you should read the wikis. May the Force be with you.
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