I may regret wading into a flame-war, but...
I got started with Python in 2002. I took one look at TKinter, said "yuck!", and went searching for something else. Now, wxPython is a bit clunky for a Python programmer because of its strong ties to C++ -- but that's what I chose, and it has served me well. I would like to see wxPython become the default GUI for our very fine programming language. -- http://mail.python.org/mailman/listinfo/python-list
