Would Python meet our requirements? I need to make lots of GUI applications (message boxes, forms, etc.) and do the underlying business logic too.
Python is my favorite language and I recommend that you experiment with it. However, if you want the quickest replacement for VB I would look at REALbasic. It has a nice IDE with an integrated GUI designer and it is generally easy for a VBer to learn. You can even convert existing VB apps as well. It won a Jolt Productivity award this year (along with Python 2.4).
http://www.realsoftware.com/index.php -- http://mail.python.org/mailman/listinfo/python-list
