Perhaps Spring Python can help you out (http://springpython.python- hosting.com). It reuses technologies like Pyro for remoting, offers database templates, has a plugable security component, an AOP solution should the need arise, an IoC container, and has a couple of web-app demos using CherryPy. Of course, you can use whatever web stack you want. I just picked CherryPy to demo things.
Each component of Spring Python is optional, and you can use it through the IoC container, or programatically. This might help you leverage development of an enterprise app. BTW, I have plans to implement a wxPython front end sample app. I just haven't done it yet. Good luck! -- http://mail.python.org/mailman/listinfo/python-list