Raghul, The second link Harlin gave is to the wxPython wiki - it has a variety of pages with information about the toolkit including a number of tutorial pages. The "Getting Started" document linked on the main page is pretty thorough. Once you comfortable with some of the basic concepts, I'd suggest looking through the wxPython demo code. Find something interesting in the demo, then look at the associated "Demo Code" tab to see how it's implemented.
In case you have any questions, the wxpython-users list is a great source of information for wxpython beginners as well as more advanced users. It's archived in a few different locations (some are easier to read or search than others): Via wxwidgets.org http://lists.wxwidgets.org/cgi-bin/ezmlm-cgi/11 Via ActiveState http://aspn.activestate.com/ASPN/Mail/Browse/Threaded/wxPython-users Via Gmane http://dir.gmane.org/gmane.comp.python.wxpython -- http://mail.python.org/mailman/listinfo/python-list