Sep 28 15:11:23 nmail spamc[4525]: connect to spamd on 127.0.0.1 failed, retrying (#1 of 3): Connection refused Sep 28 15:11:23 nmail spamc[4525]: connect to spamd on 127.0.0.1 failed, retrying (#2 of 3): Connection refused Sep 28 15:11:24 nmail spamc[4525]: connect to spamd on 127.0.0.1 failed, retrying (#3 of 3): Connection refused

Step one, is spamassasin running?
`ps aufx`

Step two, is it listening where you think it is and is the port it is listening on the port being tried?
`netstat -nlp46`

Step three, any odd firewall rules preventing connection? Highly unlikely considering localhost is nearly never blocked, but you never know. Which then leads to checking selinux rules next.

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