Wietse Venema:
> kawakami:
> > And this problem occurs NOT always, only in following situatision,
> > 
> > > 2, A message was sent on IPv4, but resuted 451 error.
> > > 3, A message was sent on IPv6, but resuted 451 error. 
> 
> After a 4xx error, the SAME  Postfix SMTP client process may
> IMMEDIATELY try to make the SAME delivery to a different MX host.
> If this is new, please read the SMTP protocol spec, RFC 5321.

And as always, DO SHOW LOGS.

        Wietse

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