Hi to everybody. Thanks for the suggestions. It's look like I've found what I was looking for...
Basically I've canceled the 'virtual_mailbox_domains', so that there are no local domains. All the internal emails are in 'transport_maps = proxy:mysql:/etc/postfix/mysql-virtual_transports.cf', where in mail_transport there all all the internal emails in a column and the word 'virtual' in the other column. If for some reason an internal email is not anymore internal, I'll change 'virtual' with nothing and that email will be relayed as external one... I've tested this solution for all the afternoon and it's look like just fine... Are some of you able to say if there is not a bad part on it that I can not see? Thanks Michele