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> Hi !
> 
> Is there any Programming Interface (api) , so that a Postfix instance
> could be accessed programmaticaly, say, a C program?

Currently,  all the SUPPORTED interfaces require that non-Postfix
code communicates with Postfix via some protocol:  examples are
the SMTP protocol, the pipe-to-command protocol, the SMTPD policy
protocol, the Milter protocol, and a simple TCP-based lookup table.

> for example, connect to a Postfix instance and validate if an e-mail
> address is a valid recipient  for the specific instance...

You can already do this with the existing SMTP interface.

        Wietse

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