Is it possible to make a header_checks rule apply only to a certain client?

I've got an annoying piece of software which sends messages through Postfix.
This software insists on including a "Sender" header that I wish to filter out 
with Postfix, but only for this certain client (or the envelope sender, which 
is always the same)
Unfortunately, fixing the software is not an option :(
Any tips?

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