Hi Andre,

I’m not totally clear what the issue is, but I can help eliminate some of the 
questions:

The original source of the data before generating the NONMEM-ready dataset is 
not important.  The formatting of the NONMEM-ready dataset is vitally important.

My guess is that your dataset includes extraneous quotation marks as created by 
the R command write.csv() (note the dot in the function name).  I would guess 
that if you use write_csv() from the readr library (note the underscore in the 
function name), it will work because write_csv() does not add extraneous 
quotation marks.

For not being able to find the data, I don’t know how Wings differs from PsN 
there, but I’d check that the data file path is correct relative to the NONMEM 
control stream.  And, I would run PsN from the same directory as the control 
stream.

Thanks,

Bill

> On Jun 27, 2019, at 06:12, Andre Jackson <[email protected]> wrote:
> 
> I have a data set for which I have experienced the following:
>  
> A Nonmem data set was prepared from SAS/R from an *.xpt file; however, when I 
> tried to run under PSN it returned that it couldn’t find the data set.
> Using a data set that I had previously prepared with SAS and run under PSN 
> (i.e., not from an *.xpt file), I  manually added additional subjects with 
> the same sampling scheme and the data set ran under PSN.  However when I 
> looked at the outputted fit file only the original subjects had been read in 
> and parameters estimated for them by PSN;
> When I run estimation with the same data set under Wings it runs okay.
>  
> Has anyone had a similar experience with data from an *.xpt file and if so 
> how can it be addressed?
>  
>  

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