Hi Sebastien, As far as I know, you could write verbatim code to generate random numbers during estimation. E.g:
$PK|$DES|$ERROR RAN = any value ; initialization "RAN = RAND(0) ; start verbatim code A random number between 0 and 1 from uniform distribution will be assigned to RAN. This function is called for each record of your input data. I believe it's also possible to call it more/fewer times through checking ICALL. Warm regards, Tingjie ________________________________ From: owner-nmus...@globomaxnm.com <owner-nmus...@globomaxnm.com> on behalf of Sebastien Bihorel <sebastien.biho...@cognigencorp.com> Sent: Thursday, May 30, 2019 12:34 To: nmusers@globomaxnm.com Subject: [NMusers] Random number generation Hi, Is it possible for NONMEM to generate a random number during an estimation run? Thank you Sebastien Bihorel