Hi Sebastien,

As far as I know, you could write verbatim code to generate random numbers 
during estimation. E.g:

$PK|$DES|$ERROR
RAN = any value ; initialization
"RAN = RAND(0) ; start verbatim code

A random number between 0 and 1 from uniform distribution will be assigned to 
RAN. This function is called for each record of your input data. I believe it's 
also possible to call it more/fewer times through checking ICALL.

Warm regards,
Tingjie




________________________________
From: owner-nmus...@globomaxnm.com <owner-nmus...@globomaxnm.com> on behalf of 
Sebastien Bihorel <sebastien.biho...@cognigencorp.com>
Sent: Thursday, May 30, 2019 12:34
To: nmusers@globomaxnm.com
Subject: [NMusers] Random number generation


Hi,

Is it possible for NONMEM to generate a random number during an estimation run?

Thank you

Sebastien Bihorel

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