Dear Markus,
I guess it depends on how you plan to make the estimation: 1) If it is by NCA, other programs will do this 2) If it is as model-based, non-linear regression, many programs will do it (incl NONMEM) 3) If you want to analyse the individual data using a previous population PK model as prior, NONMEM and other non-linear mixed effects models are probably preferable. Best regards, Mats Mats Karlsson, PhD Professor of Pharmacometrics FIRST WORLD CONFERENCE ON PHARMACOMETRICS, 5-7 September 2012, Seoul ( <http://www.go-wcop.org/> www.go-wcop.org) Dept of Pharmaceutical Biosciences Faculty of Pharmacy Uppsala University Box 591 75124 Uppsala Phone: +46 18 4714105 Fax + 46 18 4714003 From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of markus joerger Sent: 02 September 2012 04:40 To: NONMEM Subject: [NMusers] single-patient AUC dear NM-community, Is NONMEM reliably used for single-patient AUC-calculation in cases of linear PK, or is e.g. WinNonLin (or similar software) preferred in such cases? best regards, Markus -- Markus Joerger MD PhD Associate Professor Medical Oncology&Clinical Pharmacology Cantonal Hospital 9007 St. Gallen Switzerland markus.joer...@kssg.ch markus.joer...@gmail.com Phone: +41-765591070 Fax: +41-714946325
