Dear All,

I am modeling a repeated dosing study. Subjects were given twice daily doses 
for 8 weeks and a number of samples were taken on the last day of dosing. There 
were also sparse samples taken at weeks 2, 4, and 6. I want to use ADDL and II 
for the dosing scheme. Can I lump all doses into one line or do I have to stop 
the dosing record prior to each sample and re-start again? In other words, will 
the following file structure work:

ID TIME AMT   ADDL  II   DV
1    0      10      112    12   0
1    143   0         0       0   124
1    287   0         0       0   131
.
.
.

Or do I have to use the following:

ID TIME AMT   ADDL  II   DV

1    0      10      14      12   0

1    143   0         0       0   124
1    144   10      14      12   0

1    287   0         0       0   131
.
.
.

Thank you in advance.

BP





      

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