On 29 Aug 2017, at 23:24, Ryan Schmidt <ryandes...@macports.org> wrote:
> The best practice is not to do that. We don't support it. It can cause you 
> problems that we don't want to spend time investigating, because they 
> wouldn't be problems if you hadn't also used a second package manager.

You already made the same point in the list years ago.

Could you please summarize the problems one could encounter?

Aren't these actually only related to homebrew using /usr/local/?

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