It could be that your SMTP server is bound to 127.0.0.1 and not to 
192.168.2.157 (or to all interfaces, 0.0.0.0), and thus, it can accept only 
traffic arriving from the loopback (lo) interface.

You can find out to which address it is bound by using the command 
netstat -pltn.

If this is indeed the problem, simply check the configuration of your SMTP 
server and make sure it binds to 0.0.0.0...

-- Shimi

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