OK. Might have something to contribute on 2,3,7,12,16.

BTW, adding this to the paper mashup on locality: http://www.institutnicod.org/Reduction/7.OntComplSys.pdf
Backpack is getting heavy again....

C.

jstafurik wrote:
DARPA has a BAA (Broad Agency Announcement) for 23 Mathematical Challenges it would like to have researchers solve. (https://www.fbo.gov/download/9bc/9bce380aafb19f9ad3bda188bfc1ab20/DARPA-BAA-08-65.doc) Friamers should find many of these interesting, although some like "The Mathematics of the Brain" or "What are the Fundamental Laws of Biology", seem wildly ambitious:

Mathematical Challenge One: *The Mathematics of the Brain *

   *

      Develop a mathematical theory to build a functional model of the
      brain that is mathematically consistent and predictive rather
      than merely biologically inspired.

Mathematical Challenge Two: *The Dynamics of Networks*

   *

      Develop the high-dimensional mathematics needed to accurately
      model* *and predict behavior in large-scale distributed networks
      that evolve over* *time occurring in communication, biology and
      the social sciences.

Mathematical Challenge Three: *Capture and Harness Stochasticity in Nature*

   *

      Address Mumford’s call for new mathematics for the 21^st
      century. Develop methods that capture persistence in stochastic
      environments.

Mathematical Challenge Four: *21st Century Fluids*

   *

      Classical fluid dynamics and the Navier-Stokes Equation were
      extraordinarily successful in obtaining quantitative
      understanding of shock waves, turbulence and solitons, but new
      methods are needed to tackle complex fluids such as foams,
      suspensions, gels and liquid crystals.

Mathematical Challenge Five: *Biological Quantum Field Theory*

   *

      Quantum and statistical methods have had great success modeling
      virus evolution. Can such techniques be used to model more
      complex systems such as bacteria? Can these techniques be used
      to control pathogen evolution?

Mathematical Challenge Six: *Computational Duality*

   *

      Duality in mathematics has been a profound tool for theoretical
      understanding. Can it be extended to develop principled
      computational techniques where duality and geometry are the
      basis for novel algorithms?

Mathematical Challenge Seven: *Occam’s Razor in Many Dimensions*

   *

      As data collection increases can we “do more with less” by
      finding lower bounds for sensing complexity in systems? This is
      related to questions about entropy maximization algorithms.

Mathematical Challenge Eight: *Beyond Convex Optimization*

   *

      Can linear algebra be replaced by algebraic geometry in a
      systematic way?

Mathematical Challenge Nine: *What are the Physical Consequences of Perelman’s Proof of Thurston’s Geometrization Theorem?*

   *

      Can profound theoretical advances in understanding three
      dimensions be applied to construct and manipulate structures
      across scales to fabricate novel materials?

Mathematical Challenge Ten: *Algorithmic Origami and Biology*

   *

      Build a stronger mathematical theory for isometric and rigid
      embedding that can give insight into protein folding.

Mathematical Challenge Eleven: *Optimal Nanostructures*

   *

      Develop new mathematics for constructing optimal globally
      symmetric structures by following simple local rules via the
      process of nanoscale self-assembly.

Mathematical Challenge Twelve: *The Mathematics of Quantum Computing, Algorithms, and Entanglement*

   *

      In the last century we learned how quantum phenomena shape our
      world. In the coming century we need to develop the mathematics
      required to control the quantum world.

Mathematical Challenge Thirteen: *Creating a Game Theory that Scales*

   *

      What new scalable mathematics is needed to replace the
      traditional Partial Differential Equations (PDE) approach to
      differential games?

Mathematical Challenge Fourteen: *An Information Theory for Virus Evolution*

   *

      Can Shannon’s theory shed light on this fundamental area of biology?

Mathematical Challenge Fifteen: *The Geometry of Genome Space*

   *

      What notion of distance is needed to incorporate biological utility?

Mathematical Challenge Sixteen: *What are the Symmetries and Action Principles for Biology?*

   *

      Extend our understanding of symmetries and action principles in
      biology along the lines of classical thermodynamics, to include
      important biological concepts such as robustness, modularity,
      evolvability and variability.

Mathematical Challenge Seventeen: *Geometric Langlands and Quantum Physics*

   *

      How does the Langlands program, which originated in number
      theory and representation theory, explain the fundamental
      symmetries of physics? And vice versa?

Mathematical Challenge Eighteen: *Arithmetic Langlands, Topology, and Geometry*

   *

      What is the role of homotopy theory in the classical, geometric,
      and quantum Langlands programs?

Mathematical Challenge Nineteen: *Settle the Riemann Hypothesis*

   *

      The Holy Grail of number theory.

Mathematical Challenge Twenty: *Computation at Scale*

   *

      How can we develop asymptotics for a world with massively many
      degrees of freedom?

Mathematical Challenge Twenty-one: *Settle the Hodge Conjecture*

   *

      This conjecture in algebraic geometry is a metaphor for
      transforming transcendental computations into algebraic ones.

Mathematical Challenge Twenty-two: *Settle the Smooth Poincare Conjecture in Dimension 4*

   *

      What are the implications for space-time and cosmology? And
      might the answer unlock the secret of “dark energy”?

Mathematical Challenge Twenty-three: *What are the Fundamental Laws of Biology?*

   *

      This question will remain front and center for the next 100
      years. DARPA places this challenge last as finding these laws
      will undoubtedly require the mathematics developed in answering
      several of the questions listed above.


------------------------------------------------------------------------

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