Hi Daniel, Sure, why not. Group differences would be shifts/offsets of the lines for each group, while group time interaction would be different slopes.
Best, Martin On 1. Apr 2025, at 01:23, Bondi, Daniel <daniel.bo...@ubc.ca> wrote: Hi FreeSurfer experts, I am using the univariate LME pipeline (lme_fit_FS & lme_F) to conduct cortical thickness analysis on a subset of D-K atlas ROIs between two groups. Although I am testing longitudinal group*time differences with this pipeline, I am wondering if it is valid to test group-level differences (irrespective of time) with this model as well. I have been doing so by specifying only the group covariate in the contrast matrix before running the model. Thank you, Daniel Bondi _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu<mailto:Freesurfer@nmr.mgh.harvard.edu> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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