Hi Simon, The SynthMorph version in FreeSurfer 7.4.1 only supports a fixed regularization value of 1. For more adjustable regularization via the `-r` flag (and improved registration overall), I recommend the latest SynthMorph from the Docker Hub. We distribute a script that supports Docker, Podman, Apptainer, or Singularity: https://hub.docker.com/r/freesurfer/synthmorph
Alternatively, you can download a stable dev build of FreeSurfer, which includes the latest SynthMorph: https://surfer.nmr.mgh.harvard.edu/pub/dist/freesurfer/dev/stable/ Best wishes, Malte ________________________________________ From: freesurfer-boun...@nmr.mgh.harvard.edu <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Simon Jones <sp...@cam.ac.uk> Sent: Monday, October 21, 2024 13:20 To: freesurfer@nmr.mgh.harvard.edu Subject: [Freesurfer] mri_synthmorph regularisation External Email - Use Caution Dear all I tried to use change the regularisation parameter of mri_synthmorph using -s option in Freesurfer 7.4.1 but this option does not seem implemented. Is there a way to reduce the amount of regularisation? Thanks for your help, Simon **************************************************************** Mr P Simon Jones Research Associate Department of Clinical Neurosciences University of Cambridge Herchel Smith Building, Forvie Site Robinson Way Cambridge Biomedical Campus Cambridge CB2 0SZ UK **************************************************************** _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at https://www.massgeneralbrigham.org/complianceline <https://www.massgeneralbrigham.org/complianceline> . Please note that this e-mail is not secure (encrypted). If you do not wish to continue communication over unencrypted e-mail, please notify the sender of this message immediately. Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.
