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Hi Bruce, 
Thank you for your reply. On reviewing this participant in Freeview, I'm really 
not certain if there is a topological defect present, or if the WM and pial 
surface delineations are incorrect. Would it be possible to send the volume to 
you for review. If so, how would I go about this? I would greatly appreciate 
any insight you can provide. 



Kind regards, 





Bronwyn Overs 


Senior Research Assistant 



Neuroscience Research Australia 
Margarete Ainsworth Building 
Barker Street Randwick Sydney NSW 2031 Australia 
M 0411 308 769 T +61 2 9399 1725 


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From: "Fischl, Bruce R.,PHD" <bfis...@mgh.harvard.edu> 
To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu> 
Sent: Saturday, 12 October, 2024 12:42:03 AM 
Subject: Re: [Freesurfer] [WARNING: ATTACHMENT UNSCANNED]Issue with WM surface 
fill 



Hi Bronwyn 



Hard to say without seeing the data, but I would guess that there are 
topological defects causing these issues. You can overlay the locations of the 
defects in freeview and see if that explains things. 



Cheers 

Bruce 




From: freesurfer-boun...@nmr.mgh.harvard.edu 
<freesurfer-boun...@nmr.mgh.harvard.edu> On Behalf Of Bronwyn Overs 
Sent: Friday, October 11, 2024 1:31 AM 
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu> 
Subject: [Freesurfer] [WARNING: ATTACHMENT UNSCANNED]Issue with WM surface fill 




External Email - Use Caution 


Dear Freesurfer Support, 





I'm reviewing a specific MRI image that I have processed with Freesurfer V5.3. 
I'm concerned about a potential issue with voxels missing from the WM surface. 
This appears to impacting the pial boundaries and lateral ventricle labels in 
the aseg from slices 56-99. For reference, I attached 5 images (both wm and 
brainmask surfaces) that are each 5 slices apart. Happy to upload the whole 
series of images if this would be helpful. 





Would you recommend filling in some of the voxels near the lateral ventricles? 
My concern is that I am unsure where the ventricle begins, as I suspect the 
gyrus at the rh pericalcarine surface is not being properly labelled and 
identified in the pial surface. Any advice you can provide will be greatly 
appreciated. 








Kind regards, 



Bronwyn Overs 


Senior Research Assistant 








Neuroscience Research Australia 
Margarete Ainsworth Building 
Barker Street Randwick Sydney NSW 2031 Australia 
M 0411 308 769 T +61 2 9399 1725 




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