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 Alright, we were not aware of this point. Thank you very much for informing 
us. However, we would like to know your suggestion regarding rsfMRI data. Is it 
advisable to work on unprocessed data using the currently available software, 
or should we download and use preprocessed packages of HCP fMRI data? We would 
greatly appreciate it if you could answer this question. It would be very 
helpful for us.
best,Yunus
--------------------------------------------------------------------------------Yunus
 Soleymani
Ph.D. Candidate of Neuroimaging Tehran University of Medical Sciences
soleymani.yu...@yahoo.com+98 914 526 
9298--------------------------------------------------------------------------------
 

    On Monday, December 4, 2023 at 05:29:41 PM GMT+3:30, Glasser, Matt 
<glass...@wustl.edu> wrote:  
 
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FreeSurfer 7.X is not working well with HCP data right now, so your results 
will be substantially less accurate (this is being actively worked on by the 
HCP group and FreeSurfer group).  Also, FreeSurfer needs to be called as a part 
of the HCP Pipelines, not run by itself for optimal performance in HCP data.
 
  
 
Matt.
 
  
 
From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of yunus soleymani 
<soleymani.yu...@yahoo.com>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, December 4, 2023 at 7:53 AM
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] skull stripping error
 
  
 
        External Email - Use Caution        
 
Yes, you are right. However, the original HCP runs were based on Freesurfer 
version 5.3, which is an older version. Recent studies have reported 
significant differences in Freesurfer outputs across versions, especially in 
the case of cortical thicknesses. The advice is always to use the latest 
version. We plan to perform the volumetrics using version 7.4.1 of Freesurfer. 
Then, we will use both our results and the original HCP runs in our modeling, 
and maybe compare them.
 
 bests,
 
Yunus
 
  
      
  
 
  
 
On Monday, December 4, 2023 at 05:00:40 PM GMT+3:30, Glasser, Matt 
<glass...@wustl.edu> wrote:
 
  
 
  
 
        External Email - Use Caution        
 
Why are you rerunning FreeSurfer on HCP data?  You are unlikely to match the 
quality of the original FreeSurfer runs.
 

Matt.
 
 
 
From:<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of yunus soleymani 
<soleymani.yu...@yahoo.com>
Reply-To: Freesurfer Support List <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, December 4, 2023 at 4:59 AM
To: Freesurfer Support List <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] skull stripping error
 
 
 
        External Email - Use Caution        
 
 
 
Hello Freesurfers,
 
 
 
I recently analyzed about 600 subjects from HCP database using the Freesurfer 
recon-all algorithm. However, I noticed that in almost one third of the 
subjects, the software did not perform the skull stripping correctly when I 
checked the results in Freeview. To address this issue, I repeated the skull 
stripping step for each subject using the code "recon-all -skullstrip -wsthresh 
35 -clean-bm -s <subject name>". The skull stripping went well, and then I 
repeated the analysis using the code "recon-all -autorecon-pial -subjid 
<subject name>".
 
 
 
When I compared the pre and post-correction stats folder, I noticed that some 
volumetric values had changed, especially in the specific areas related to the 
initial skull stripping error. However, my concern is that when I loaded the 
.pial and .aseg files into Freeview, there was no change compared to before the 
correction visually. Is this okay, or should I take additional steps? I would 
appreciate your help.
 
 
 
Thank you,
 
Yunus
 Bellow is an example. NumberS 1 and 2 are brain masks before and after 
correction. Numbers 2 and 3 are superimposed .aseg files before and after 
correction. 
 
 
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