External Email - Use Caution        

Sorry, missed this one before I got the personal invitation to respond.

I believe this would use a FreeSurfer registration of the group parcellation to 
the individual.  That is a folding-based registration and one can do slightly 
better than that with MSMSulc.  One can do much better than that with MSMAll, 
which is an areal-feature-based registration.  Finally, a direct areal 
classifier can do even better, and we are working on a new version of that that 
is more shareable.  Also, there will likely be improvements to the various 
registration methods in the future.  Coalson et al., (2018) PNAS has some 
comparisons of different approaches currently available.

Matt.

From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of "Boa Sorte Silva, 
Narlon" <narlon.si...@ubc.ca>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, November 27, 2023 at 4:20 PM
To: freesurfer <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] FreeSurfer Parcellation Using Glasser's Atlas (HCP-MMP1)


Hi there,

I am hoping to extract cortical thickness and volume data from 
FreeSurfer-processed subjects using the HCP-MMP1 atlas (Glasser et al 2016 
Nature). I have found many discussions in the email list but I wasn’t able to 
understand whether this procedure can be reliably done using .annot files.

I have found ?h.HCPMMP1.annot files online (e.g., ggsegGlasser: MailScanner has 
detected a possible fraud attempt from "secure-web.cisco.com" claiming to be 
https://secure-web.cisco.com/1JmbBV86Tak0d8hlYwX2j2lbFduvB1TXb8SuiSz1dCoDi3wgWSA2r8PPrMsq0l8bbJAsBf9uT1mISw766iTyCDnBY4K5vDesWZqy9gJLdMsAxZQTwNLsrx-6fmPx5ebEJeyJ2wqBna4CLjyZnI-Xb7qKpk6TbZP6uUHp5ryhBDAdPOOgGXtJhufoAr8GVNkja5UslPyPbUAslOc6dt5Ql--o3bCH7eonOMmbKbnKC2BgCKY2kmDE6Qx4fqMmzASQw6Jb-zNKjQfKINTqCBGP9oc69eqFsCzpbk5ConWs6e_w8fUOg5IjsCUq2PY4EzV1t/https%3A%2F%2Fgithub.com%2Fggseg%2FggsegGlasser%2Ftree%2Fmaster%2Fdata-raw<https://secure-web.cisco.com/1RCrRYR2kfqIYN7pxC6sGgF_XvdqzAAephS3DadIADfMm-6hoRd0sxcmdWRwYcGtkA-1gc7ZC9mYwzkPFHM8ycIPc3lYKBliI4MlhpBI0pNP7d6nNXhKmziozV7LPHR6bOmLuljZCo6Elu5DfPrDjcK9sXxOTADtFMn_j7QiamMngwTj6ci-kK7weiVMNm48V-1lppYtYxYIF2o33pH_y3e0U1uQqglVKzEK9L4W50PlIBDYIetkga5KuLV3JZ3qULjZufEAQgsKcBIZ09jnE1GKxMWrAVDgQWUqbas9gFiJnELS_7FBm92O9x6kP22Zn/https%3A%2F%2Fgithub.com%2Fggseg%2FggsegGlasser%2Ftree%2Fmaster%2Fdata-raw>)
 in fsaverage space, which I have resampled to the subject’s space using 
mri_surf2surf  as follows:

 # Apply Glasser’s 2016 HCP-MMIP1.0 atlas
mri_surf2surf \
--hemi ${hemi} \
--srcsubject fsaverage \
--trgsubject ${id} \
--sval-annot fsaverage/label/${hemi}.HCPMMP1.annot \
--tval ${SUBJECTS_DIR}/${id}/label/${hemi}.HCPMMP1.annot


Then I extracted the stats using this command:

# Extract Thickness and Volume stats
mris_anatomical_stats \
-a ${SUBJECTS_DIR}/${id}/label/${hemi}.HCPMMP1.annot \
        -f ${SUBJECTS_DIR}/${id}/stats/${hemi}.HCPMMP1.stats \
        -b ${id} ${hemi}

My question is whether the output from this procedure can be reliably used as 
an accurate version of the HCP-MMP1 parcellated regions in the subject’s native 
space OR whether a more involved process is needed to generate the parcellation.

Thank you for your help

Best regards,
Nárlon Cássio

Nárlon C Boa Sorte Silva PhD (He, Him, His)
CIHR and MSHR BC/CLEAR Postdoctoral Research Fellow
Aging, Mobility, and Cognitive Health Lab
Djavad Mowafaghian Centre for Brain Health
Department of Physical Therapy, Faculty of Medicine
University of British Columbia
Vancouver, Canada
Twitter: @BoaNarlon


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