External Email - Use Caution        

Hi Doug,

The FSGD looks like the attached. For the contrast: [ 0 0 0 0 0.5 -0.5 -0.5
0.5 0 0 0 0], to model the 3-way interaction between Class and the new
multiplied continuous interaction variable controlling for eTIV.

That brainmap, where we multiply the two continuous variables, is not as
robust as the original one where I tried to do the 3-way interaction
between the 3 variables (2 continuous, 1 categorical (class)). So I really
wonder what it was actually doing/plotting on the surface exactly? (ROIa x
ROIb x class + eTIV:  [0 0 0 0 0.25 -0.25 -0.25 0.25 0.25 -0.25 -0.25 0.25
0 0 0 0]). Was it considering every row of the continuous variable as a
category or? Would be great to be able to use that map (with the covariates
normalized).

Thank you so much for your help!

All the best,

Fred


On Mon, May 1, 2023 at 8:48 AM Douglas N. Greve <dgr...@mgh.harvard.edu>
wrote:

>         External Email - Use Caution
>
> not sure, what you're new FSGD is
>
> On 4/28/2023 1:23 PM, Federico Uquillas wrote:
>
>         External Email - Use Caution
> Thank you so much!
>
> Okie doke.
> So then, for an interaction between gender x handedness x
> ROIsInteractionTerm (continuous), controlling for eTIV, the contrast would
> be the following?
>
> [ 0 0 0 0 0.5 -0.5 -0.5 0.5 0 0 0 0]
>
> All the best,
>
> Fred
>
> On Apr 28, 2023, at 10:30 AM, Douglas N. Greve <dgr...@mgh.harvard.edu>
> <dgr...@mgh.harvard.edu> wrote:
>
>         External Email - Use Caution
> The method you describe is only for discrete variables, not continuous
> ones. The traditional method for continuous variables is to create a new
> variable where you multiply them together. You should normalize you
> continuous variables too (ie, subtract the mean and divide by the stddev).
>
> On 4/24/2023 8:52 PM, Fred d'Oleire Uquillas wrote:
>
>         External Email - Use Caution
> Dear Fs support,
>
> If I have the following FSGD with 4 classes and 3 variables, and I'd like
> to run an interaction of ROIa x ROIb controlling for the third covariate
> (eTIV), would I use the following contrast?
>
> [0 0 0 0 0.25 -0.25 -0.25 0.25 0.25 -0.25 -0.25 0.25 0 0 0 0]
>
> For the interaction of ROIa x ROIb x class + eTIV.
>
> Thank you so much in advance for your help!
>
> All the best,
>
> Fred
>
>
>
>
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GroupDescriptorFile     1                       
Title nameoffsgdfile.fsgd                               
Measurement volume                              
                                
Class A_F                               
Class A_M                               
Class B_F                               
Class B_M                               
                                
Variables  ROIa_x_ROIb  eTIV                            
                                
Input   sub1    A_F     -0.558508973    -0.459629971
Input   sub2    A_M     -1.331036609    0.356666603
Input   sub3    A_F     0.441320898     -0.82728237
Input   sub4    A_M     1.889119186     -0.289027846
Input   sub5    A_M     0.483409205     0.910894535
Input   sub6    A_F     1.176957731     0.889841343
Input   sub7    B_M     1.141435488     -0.215874666
Input   sub8    B_M     1.094023759     -0.311508301
Input   sub9    B_F     -0.662756296    -1.458631419
Input   sub10   B_F     -0.545566602    1.093101204
Input   sub11   B_M     1.358897112     0.036309049
Input   sub12   B_M     -0.230924767    2.192369656
Input   sub13   A_M     2.912504752     0.038401394
Input   sub14   A_M     0.527775599     0.041363153
Input   sub15   A_F     2.076428966     -1.04946053
Input   sub16   B_M     1.042692642     0.007268707
Input   sub17   A_M     0.056222676     -0.542067302
Input   sub18   A_M     0.841005288     0.639406339
Input   sub19   A_M     0.233779194     -0.815182696
Input   sub20   A_M     0.460240219     -1.660856407
Input   sub21   A_F     1.154944564     0.971822467
Input   sub22   A_M     0.683315585     -0.722698189
Input   sub23   A_M     0.231664237     0.787856776
Input   sub24   A_F     3.811859561     2.702007823
Input   sub25   A_F     0.089570571     -0.040201369
Input   sub26   A_M     0.152098438     -1.057373017
Input   sub27   A_M     -0.22237588     -1.523449866
Input   sub28   A_M     -1.204555212    -0.582728093
Input   sub29   A_M     -1.355385866    -0.467477626
Input   sub30   A_M     -0.221394449    0.439262559
Input   sub31   A_M     -0.682891251    1.639540621
Input   sub32   A_M     -0.909509019    -1.528419298
Input   sub33   A_M     -1.359884386    -1.017446521
Input   sub34   A_M     -2.223458774    -0.048471683
Input   sub35   A_M     0.054403342     -1.786514816
Input   sub36   A_M     -0.418103729    -0.875094498
Input   sub37   A_M     -0.599931644    0.462872046
Input   sub38   A_M     0.050085881     -1.943489327
Input   sub39   A_M     -0.197669322    -0.308628534
Input   sub40   A_M     -2.187695152    -0.621722948
Input   sub41   A_M     -1.779360985    -1.358832972
Input   sub42   A_M     -1.473471178    -0.197504881
Input   sub43   B_M     -0.167132704    0.329204724
Input   sub44   B_M     -0.881498636    0.470516521
Input   sub45   B_F     0.058354054     -0.919763768
Input   sub46   B_M     0.533667494     0.514545008
Input   sub47   B_F     -0.021673492    -1.40729398
Input   sub48   B_M     -0.01836036     -1.005684483
Input   sub49   B_F     -0.064682257    -0.3773586
Input   sub50   B_M     -0.634375091    -0.741874878
Input   sub51   B_M     -1.041314502    -0.403571436
Input   sub52   B_M     -0.118782385    -1.053155366
Input   sub53   B_M     -0.08555539     -1.133303388
Input   sub54   B_F     1.216696054     -0.23315161
Input   sub55   B_M     -0.35611296     -0.502389626
Input   sub56   B_M     -0.429048454    -0.761716192
Input   sub57   B_M     0.403296336     -0.428687073
Input   sub58   B_F     1.355892779     0.389198051
Input   sub59   B_M     -0.718340721    -1.448367411
Input   sub60   B_M     0.315109682     0.712188121
Input   sub61   B_F     -0.579496419    0.183179936
Input   sub62   B_F     -0.250758126    -1.12675531
Input   sub63   B_M     -0.123314921    -0.388876941
Input   sub64   B_M     -0.161780636    -0.213173458
Input   sub65   B_M     0.141733231     0.073075386
Input   sub66   A_M     0.432923712     -0.353396974
Input   sub67   A_M     -1.346142323    0.168029211
Input   sub68   A_M     0.24155056      0.019615493
Input   sub69   A_M     0.901871455     -0.818525605
Input   sub70   A_M     0.100768158     -0.488015575
Input   sub71   A_M     0.109320394     0.098898925
Input   sub72   A_M     0.400916        -0.714700714
Input   sub73   A_F     -1.132843849    -1.213406935
Input   sub74   A_F     -0.141064718    0.516948097
Input   sub75   A_F     -0.040498845    0.137942811
Input   sub76   A_M     -0.921629059    -0.909880512
Input   sub77   B_M     -0.767759297    -0.141557761
Input   sub78   B_M     -0.589730682    -0.343782414
Input   sub79   A_F     1.22787431      -0.199929564
Input   sub80   A_M     0.156077919     0.448331315
Input   sub81   A_M     0.839575179     0.765864939
Input   sub82   A_M     0.951659951     0.053268833
Input   sub83   A_M     0.958343077     2.911224225
Input   sub84   A_M     -0.19921048     -0.893717179
Input   sub85   B_M     -0.159838907    1.952798668
Input   sub86   B_F     -0.318073565    -0.15917407
Input   sub87   B_M     0.616824725     3.216486493
Input   sub88   B_M     0.113012441     -0.699799218
Input   sub89   B_M     -1.050783382    1.963823258
Input   sub90   A_M     0.364593121     -0.105686711
Input   sub91   A_M     0.007063235     0.213975389
Input   sub92   A_M     0.127037717     -1.421979193
Input   sub93   A_M     -0.325222204    -0.051393687
Input   sub94   A_M     0.387187774     -0.133677909
Input   sub95   A_F     1.262565864     -0.955338612
Input   sub96   A_F     -0.464024548    -0.715677454
Input   sub97   A_M     -0.751319042    -0.736590239
Input   sub98   A_M     0.615137932     0.30999935
Input   sub99   A_M     -0.181322686    -0.123073549
Input   sub100  A_M     0.278775077     0.596732017
Input   sub101  A_M     -0.10199299     0.277199128
Input   sub102  A_M     0.206977107     -0.597842798
Input   sub103  A_M     0.342215146     -0.296809144
Input   sub104  B_M     -0.207022453    -1.057072692
Input   sub105  B_M     -0.628894527    -1.263285637
Input   sub106  B_M     0.430343694     0.585558005
Input   sub107  B_M     -0.022559871    -0.177430958
Input   sub108  B_M     -0.279393192    -0.201083289
Input   sub109  B_M     0.498183145     0.255849307
Input   sub110  B_M     1.334373966     -0.342576588
Input   sub111  B_F     1.379940515     -0.84664312
Input   sub112  B_F     -1.093370588    -0.749949468
Input   sub113  B_M     -0.875894605    -0.701967042
Input   sub114  B_M     -0.059762264    -0.067772264
Input   sub115  B_M     2.708684908     0.374546736
Input   sub116  B_M     2.584487752     -0.569405118
Input   sub117  B_M     -0.201872685    -0.080819579
Input   sub118  B_F     1.184245837     -0.39744742
Input   sub119  B_M     -0.603680653    -0.857378217
Input   sub120  B_F     -0.214282254    -0.702876036
Input   sub121  B_M     1.071309526     0.532219907
Input   sub122  B_F     0.34591541      0.125957306
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