External Email - Use Caution No, it does not affect it. The ICV is actually and *estaimated* ICV derived from the registration of the T1 to MNI305 space, so the T2 does not come into play.
On 4/17/2023 2:11 PM, Steven Meisler wrote: > External Email - Use Caution > > Hi FS team, > > I am running a morphometry study on a public dataset with most, but not all, > subjects having a T1 and T2 (about 75% have both, remaining only have T1). To > get the best surfaces possible, I have been including the T2 in recon-all > process when able to. However, this means subjects with only a T1 have > underwent a different processing workflow. ICV is an important predictor in > my study, and I was wondering if the presence of the T2 image in recon-all > should impact the ICV estimates? As I see it, I have the following options: > > 1) T2 is a factor, so I use only include T1 in recon-all so all subjects have > the same pipeline > 2) T2 is a factor, so I harmonize the data as I would with data from > different sites/scanners > 3) T2 is a factor, so I only analyze subjects with T1 + T2 > 4) T2 is not a factor, just use all subjects with no special considerations > > I am also running vertex-wise surface based morphometry, where I imagine pial > refinements could be more impactful. I suppose in that case, I should > harmonize the morphometry data, but was curious if you think something like > that is necessary. > > Thank you, > Steven Meisler > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://secure-web.cisco.com/1iAD3fj03-Svj5Q9Ac12rWbor-MUY4-pHjCtS5cnKdh5NnyyUlqUfQSvFAKEExPA3c1zOhI4ENTETnZ5MBCMqGSgZ0hQAfBpVb4Q5pa8AaFxpw7VswJwlFlmQOMb5lYQefSEGOwqeWPKw6JMK6M2A0aO5XegyIW1VFSKgqI2MHDNfRCLHPCrQYJcFDlIeKPJRs8H7kCONbGBGEmbROfeu3fS5hP6olf3lcYhYsYR9SFYrP3smNSvoSjTSi96UQc9czWZ_VZKSjQ1VXBNNboIqtA/https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at https://www.massgeneralbrigham.org/complianceline <https://www.massgeneralbrigham.org/complianceline> . Please note that this e-mail is not secure (encrypted). If you do not wish to continue communication over unencrypted e-mail, please notify the sender of this message immediately. Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.
