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Freesurfer seem to be able to do it very well when I add the FLAIR and T2
scans. These have better axial resolution (up to 570x570) but there are
only 30 slices yet the results dramatically improve,

1) Can I, with freesurfer, add a second, different, T2 scan (again high
resolution in 2D but only 30 slices)
2) Can I, with freesurfer,  add another T1 scan  (also high resolution in
2D but only 30 slices)

Michael


On Fri, Mar 31, 2023 at 12:48 PM Glasser, Matt <glass...@wustl.edu> wrote:

>         External Email - Use Caution
>
> I think there are some deep learning approaches out there that try to
> infer a high-resolution volume from low resolution volumes in multiple
> planes.  I don’t know if they would work with only axial and sagittal
> images though.
>
>
> Matt.
>
>
>
> *From: *<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Michael Mc
> Laughlin <mich...@thecurate.com>
> *Reply-To: *Freesurfer support list <Freesurfer@nmr.mgh.harvard.edu>
> *Date: *Friday, March 31, 2023 at 6:36 AM
> *To: *Freesurfer support list <Freesurfer@nmr.mgh.harvard.edu>
> *Subject: *[Freesurfer] Is it possible to add additional T1 scans to
> improve surfaces/segmentation
>
>
>
> *        External Email - Use Caution        *
>
> I am working with standard neuro radiological MRI scans.
>
>
>
> These typically have something like this::
>
>
>
> a)  T1 headscout volume: 1.6mmx1.6mmx1.625mm   160x160x128
>
> b)  T1 se tra 0.72x0.72x5.2 320x320x30
>
> c)  T2 tse tra scan 0.72x0.72x5.2 320x320x30
>
> d)  T2 FLAIR (dark fluid) scan  0.58x0.58x5.2 460x460x30
>
> c)  T1 tse sag 0.72x0.72x5.2 320x320x30
>
> c)  T2 tse sag 0.72x0.72x5.2 320x320x30
>
>
>
> I have found that the best results are obtained if I do the following:
>
>
>
> i) Start with the T1 headscout volume: 1.6mmx1.6mmx1.625mm
>
> This produces poor pial results but much better than using the T1s with a
> small number of slices.
>
> ii) Add in the flair data: Use -FLAIR and -autorecon3 with a FLAIR MRI scan
>
> This dramatically improves the pial surfaces and they look almost normal
>
> iii) Add some T2 data.
>
> This give more improvement of the pial surfaces
>
>
>
> See attached image for how the cortex looks after these stages
>
>
>
> My questions are:
>
>
>
> *1) How can I add in the data from the higher resolution T1 scans? (with
> only 30 slices)*
>
>
>
> *2) If I add a second T2 scan with -T2 -T2pial -autorecon3  will the
> results improve even more?*
>
>
>
>
>
> Regards,
>
> Michael
>
>
>
>
>
>
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