External Email - Use Caution        

export SUBJECTS_DIR=<path to your recons>

mri_cnr $SUBJECTS_DIR/<subject name>/surf/ $SUBJECTS_DIR/ <subject name>
/mri/norm.mgz > output_CNR.txt
wm-anat-snr --s <subject name> check stats/wmsnr.e3.dat .... the output is
snr for the whole white matter.

if you need snr for every roi in aseg.stats or wmparc.stats, then you can
add the flag --snr to the command mri_segstats as follows:

mri_segstats --seg mri/aseg.mgz --sum stats/aseg.stats --pv mri/norm.mgz
--empty --brainmask mri/brainmask.mgz --brain-vol-from-seg --excludeid 0
--excl-ctxgmwm --supratent --subcortgray --in mri/norm.mgz
--in-intensity-name norm --in-intensity-units MR --etiv --surf-wm-vol
--surf-ctx-vol --totalgray --euler --ctab
/usr/local/freesurfer/6.0/ASegStatsLUT.txt --subject <subjectname> --snr

do the same for wmparc.stats:
mri_segstats --seg mri/wmparc.mgz --sum stats/wmparc.stats --pv
mri/norm.mgz --excludeid 0 --brainmask mri/brainmask.mgz --in mri/norm.mgz
--in-intensity-name norm --in-intensity-units MR --subject <subjectname>
--surf-wm-vol --ctab /usr/local/freesurfer/6.0/WMParcStatsLUT.txt --etiv
--snr

make sure to change /usr/local/freesurfer/6.0/ASegStatsLUT.txt  in the
previous command to the FS folder on your system

The last two commands update aseg.stats and wmparc.stats. They both will
get a new column for SNR values for every roi.


On Fri, Feb 10, 2023 at 10:25 PM MANSON ERIC NAAB <enman...@st.ug.edu.gh>
wrote:

>         External Email - Use Caution
>
> Thank you very much for your quick response. I still have a challenge
> locating the output file after running the suggested  command
> ( mri_cnr $SUBJECTS_DIR/bert/surf/ $SUBJECTS_DIR/bert/mri/norm.mgz) with
> my subject.
> Can you please provide me with the full command for calculating
> contrast-to-noise ratio and signal-to-noise ratio of white matter, gray
> matter and CSF since am a beginner Or a video link to calculate them.
>
> This is what i see after running the command
>
> mri_cnr /Applications/freesurfer/7.1.1/SUBNEW/PA1//label/lh.cortex.label
>
> mri_cnr -- compute the gray/white/csf contrast-to-noise ratio for volumes.
>
> usage: mri_cnr [options] <surf directory> <vol 1> <vol 2> ...
>
> usage example (assumes fs pipeline has finished for subject subj1):
> mri_cnr subj1/surf subj1/mri/orig.mgz
>
> Available options:
>
> -s <slope_fname> <dist in> <dist out> <step in> <step out>: compute slope
> based on given values, write it to slope and offset files labeled
> <slope_fname> (e.g., `lh.<slope_fname>.slope.mgz')
>
> -t : print only the total CNR to stdout (stderr still contains more
> information)
>
> -l <logfile>: log cnr to file <logfile>. Will contain 8 values in the
> following order: gray_white_cnr, gray_csf_cnr, white_mean, gray_mean,
> csf_mean, sqrt(white_var), sqrt(gray_var), sqrt(csf_var)
>
> label <lh> <rh>: read hemisphere labels from <lh> and <rh>
>
> -u, -?, -help : print usage information and quit
>
> -version : print software version information and quit.
>
> On Thu, Feb 9, 2023 at 3:46 PM John Anderson <jb19790...@gmail.com> wrote:
>
>>         External Email - Use Caution
>>
>> You might consider the command wm-anat-snr to compute SNR
>>
>> On Thu, Feb 9, 2023 at 10:38 AM Kumar, Avnish <
>> avnish.ku...@mgh.harvard.edu> wrote:
>>
>>> You could also use these:
>>>
>>>    1. For CNR you can use the mri_cnr tool:
>>>
>>> mri_cnr [options] <surf directory> <vol 1>
>>>
>>> For example:
>>>
>>> mri_cnr $SUBJECTS_DIR/bert/surf/ $SUBJECTS_DIR/bert/mri/norm.mgz
>>>
>>>
>>>
>>>    1. For SNR, you'll have to calculate them as:
>>>       1.
>>>
>>>       Run the recon-all pipeline to process your MRI data.
>>>       2.
>>>
>>>       Use the mri_binarize tool to create a binary mask of the ROI in
>>>       the image.
>>>       3.
>>>
>>>       Use the mri_segstats tool to calculate the mean and standard
>>>       deviation of the intensity values within the ROI.
>>>       4.
>>>
>>>       Then your SNR = mean_intensity/std_of_intensity.
>>>
>>>
>>> Best,
>>>
>>> Avnish
>>> ------------------------------
>>> *From:* freesurfer-boun...@nmr.mgh.harvard.edu <
>>> freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Huang, Yujing <
>>> yhuan...@mgh.harvard.edu>
>>> *Sent:* Tuesday, February 7, 2023 9:09 AM
>>> *To:* Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
>>> *Subject:* Re: [Freesurfer] MRI image quality metrics
>>>
>>>
>>> Hi,
>>>
>>>
>>>
>>> The following is taken from *MailScanner has detected a possible fraud
>>> attempt from "secure-web.cisco.com" claiming to be*
>>> https://secure-web.cisco.com/15IwpbwQA-WCW8yltQ1qpLfRaQV-8nx8afnQdmUW16GAXDwTUuUE2Uo7ja53lo5m7QrlaFd47dzyShd9KzRS2Es1vj-OVv2KNK8YwnrKMk_THG1mncORT2zcXT-2Z1CQSXJ4fFOwfPkWc8YM1bqAMvG6W_r9RBMqgVA7Jy3u04DIz5Zoov1ua2fuerdE_bRqfR8Qv_7aKjopsHnq6DmBpW392U8ds0q4m2dZ3_ztQfJIqJyH4PPd0ovHK46IAJ7zYw4Ssh70e0XtUfztdvLQFQjVeFQtJkc-E2Kq6USLv6B8cuoQG2e1PO4hoVZ1AhMkJCRIj1tFy8QWMhNJ2s_BUrQ/https%3A%2F%2Fgithub.com%2FComaRecoveryLab%2FLesion_Correction
>>> <https://secure-web.cisco.com/1thfo9hWCJUK_nYfNM9axD5kjhrzv1nVC_cWmWT2aic2ttFqLtKhuhi9E6AA5fXRqlBpbp24-HV_sfbVQik2RJDyE7c9eALg8zbpl340Dwhl2aijQIJcCFqj9K_RZhk5xCVRHURT36bgdsm5C36VxQ3fQh7sVLpsmxKo0Ie0hB8HrgI8Rn7JySIK5iCJZWL9q1OqnFWJgdRUgMDrVlJVf356x-vM1sz0IWVGsGErBQNdxLAYcSvFCTWx0fb6tb1mCw7ljDzERXM7qU-fnbvpV-AKWSuj0eVKouZoNRp8SgTUOIA2mR_VbqAJw9K2PU4OKa4g3f30QsCJpd0U1hcNz7Q/https%3A%2F%2Fgithub.com%2FComaRecoveryLab%2FLesion_Correction>
>>> as mentioned in this paper *MailScanner has detected a possible fraud
>>> attempt from "secure-web.cisco.com" claiming to be*
>>> https://secure-web.cisco.com/1yJ_L006xWsJhmlYzv5RmfhdySC-5IeAYuWn6pMVGtU1ScZSh4dbdq0Q00DqNIYarr5afo262h72-7niJXMcaNnhgVOsYFRHiTX7nl6URCYU_ZyxCOcXrJM7aLIjjmS6HVFtmzIKpFqj6xaeKJXzQGtuNzdH2Dw5kx8I6INI19xyZ7k3ueNDIKrpdSNZ9JMhb7_RMrhCsKNCnuRPQJdx4oQN_7OmZg2C8hg2Lna4GDZG_8PlJn-qFRlSD9lV6nsV5pwHaE9nr2M2NUtOH7yeHC2j9BQovgiKN1ogVexEhjWXYGWTr3j1m3c6Dj-7qSFMeWpTywHvGJPstr-EnNAdWoQ/https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FS2215016120302144
>>> <https://secure-web.cisco.com/1aMzZKpIcKTLwbYP_79ZqCUH8p9h0Xh4xqpm8fsmVREKN8hATdl6DHCSkFDKqidqmKqoAydr5eDqjVLAQDKN0zmR2k2Wckx-sv1P3JgKJVQWfpIVeyrh0tqwnGzqQm3nK9BQGA7rUSYwaCBBjmogAhlrnepeAo1_J0CQXj4rKMM-V_g9sXIIirV1h-sajPjULI9qcQw2orS-vs9tl65xAbfrEtmtZ35-IZO43Wk-1D2CsVkFyKCsuGxT5qcGTg9FV3VSUbHpeA-dKS1qkv8zYKtz4i-JeRm0y4E6YAs_B91ccue5fFsCAMyN4jKTPxkhNk7f7IRaIrbfA6GYyWFCX7A/https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FS2215016120302144>
>>>
>>>
>>>
>>> “
>>>
>>> Qualitative and Quantitative Assessment of MRI Data
>>>
>>>
>>>
>>> SNR: We calculated SNR for each subject using the “wm-anat-snr”
>>> FreeSurfer tool available in FreeSurfer v6.0. Voxels from the subject’s
>>> normalized T1 (norm.mgz) that containing white matter (WM) as defined by
>>> the subject’s aparc+aseg.mgz are used to calculate SNR with this tool.
>>>
>>>
>>>
>>> SNR = (mean WM)/(stdev WM)
>>>
>>>
>>>
>>> We ran the following command for each subject:
>>>
>>>
>>>
>>> wm-anat-snr –s
>>>
>>>
>>>
>>> CNR: We calculated CNR for each subject using the “mri_cnr” FreeSurfer
>>> tool available in FreeSurfer v6.0. This tool finds the average between two
>>> CNRs: the subject’s (1) WM and gray matter (GM) CNR and (2) gray matter and
>>> cerebrospinal fluid (CSF) CNR. The average CNR is then calculated and
>>> reported for each hemisphere. Finally, the CNR for both hemispheres are
>>> averaged to produce a full brain CNR.
>>>
>>>
>>>
>>> WM-GM CNR = (delta(WM,GM)^2)/(total variance) GM-CSF CNR =
>>> (delta(GM,CSF)^2)/(total variance) Hemisphere CNR = (WM-GM CNR + GM-CSF
>>> CNR) x 2 Full Brain CNR = (Left Hemisphere CNR + Right Hemisphere CNR) x 2
>>>
>>> “
>>>
>>>
>>>
>>>
>>>
>>> Best,
>>>
>>>
>>>
>>> Yujing
>>>
>>>
>>>
>>> *From:* freesurfer-boun...@nmr.mgh.harvard.edu <
>>> freesurfer-boun...@nmr.mgh.harvard.edu> *On Behalf Of *MANSON ERIC NAAB
>>> *Sent:* Tuesday, February 7, 2023 5:26 AM
>>> *To:* Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
>>> *Subject:* [Freesurfer] MRI image quality metrics
>>>
>>>
>>>
>>> *        External Email - Use Caution        *
>>>
>>> Dear FreeSurfer experts,
>>>
>>> Please, I need your assistance and guidance on calculating the
>>> contrast-to-noise ratio (CNR) and signal-to-noise-ratio (SNR) of White
>>> matter, Gray matter, and CSF of the brain after recon-all.
>>>
>>>
>>>
>>> Thank you
>>> _______________________________________________
>>> Freesurfer mailing list
>>> Freesurfer@nmr.mgh.harvard.edu
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>>> .
>>>
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