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We showed improved data (more accurate surface placement leading to more
accurate myelin maps) in prior publications (Glasser et al., 2013; 2014
Neuroimage). It makes a difference for cortical thickness too (e.g., falsely
too low cortical thickness in auditory cortex in Glasser and Van Essen 2011
Journal of Neuroscience). That said, at least in our hands we have had some
issues with FreeSurfer 7.X and the hires stream. I’ve been hoping that the FS
folks have a chance to investigate that soon, but for now we have stuck with FS
6.0 for the HCP and HCP Pipelines.
In general, it’s good to have at least two voxels of grey matter for even the
thinnest cortical areas (e.g., somatosensory area 3b, visual area V1), which
are about 1.6mm thick. This is where the HCP’s recommendation of at least
0.8mm isotropic T1w and T2w or FLAIR images comes from (and why we didn’t stick
with the typical 1mm resolution recommendation that was prevalent before the
HCP).
Matt.
From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of "Lee, Sang Hoon"
<lsa...@med.miami.edu>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Monday, January 30, 2023 at 9:22 AM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] High resolution T1
External Email - Use Caution
I understand that from Version 7.0, better high resolution surface
reconstruction with -hires is done.
My question is, if we use higher resolution T1, such as 0.8mm, will it improve
the accuracy of the cortical thickness measurement? If yes, is there any
reference?
Thank you so much for your time!
Sang H. Lee (Sr. Research Associate III)
UM-Millier School of Medicine
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