External Email - Use Caution        

On other thought: You may want to do Doug's suggestion of calculating the
paired-diff in the longitudinal stream's subject-specific unbiased template
space of each participant instead of doing it all in fsaverage. Then take
the resultant file, the symmetrized percent change, or pc1, etc. from the
subject-specific template space to fsaverage for your group statistics.

On Wed, Sep 21, 2022 at 12:39 PM Gomar, Jesus <jgo...@northwell.edu> wrote:

>         External Email - Use Caution
>
> Thank you Doug, I will follow your suggestion.
>
>
>
>
>
> *From:* freesurfer-boun...@nmr.mgh.harvard.edu [mailto:
> freesurfer-boun...@nmr.mgh.harvard.edu] *On Behalf Of *Douglas N. Greve
> *Sent:* Wednesday, September 21, 2022 9:58 AM
> *To:* freesurfer@nmr.mgh.harvard.edu
> *Subject:* [EXTERNAL] Re: [Freesurfer] Longitudinal PET analysis
>
>
>
> *External Email. Do not click links or open attachments unless you trust
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>
> You may be able to use one of the paired diff options in mris_preproc. Run
> it with --help. I also put some info on it below. QDEC has been deprecated
>
>
>
> --paired-diff
>
> After concatenating all the inputs together, create a new output file by
> computing paired differences, ie, Input1-Input2, Input3-Input4, etc.
> There must be an even number of inputs. The inputs are "pruned" before
> taking the difference, meaning that values for all inputs are set to 0
> if any individual is 0.
>
> --paired-diff-norm
>
> Same as --paired-diff, but normalizes by average of time points, ie,
> (Input1-Input2)/((Input1+Input2)/2).
>
> --paired-diff-norm1
>
> Same as --paired-diff, but normalizes by time point 1, ie,
> (Input1-Input2)/Input1.
>
> --paired-diff-norm2
>
> Same as --paired-diff, but normalizes by time point 2, ie,
> (Input1-Input2)/Input2.
>
>
> On 9/20/2022 3:31 PM, Gomar, Jesus wrote:
>
> *        External Email - Use Caution        *
>
> Hello Freesurfer developers,
>
>
>
> I am interested in analyzing PET data following a longitudinal design.
>
> I have co-registered each PET image to the closest MRI in time processed
> through the longitudinal stream.
>
> I have sampled each co-registered PET image time-point onto fsaverage
> surface via the individual's subject surface (mri_vol2surf).
>
> From this point:
>
> 1.       Is it possible to obtain spc (symmetrized percent change) using
> long_mris_slopes for each subject?
>
> 2.       Is there a way to input the sampled surfaces into a qdec file
> for long_mris_slopes command?
>
>
>
> 1) FreeSurfer version: freesurfer-linux-centos6_x86_64-7.2.0.
>
> 2) Platform: Ubuntu 18,04.6 LTS
>
> 3) uname -a: Linux ubuntu 5.4.0-122-generic-Ubuntu UTC 2022 x86_64 x86_64
> x86_64 GNU/Linux
>
>
>
>
>
> Thank you!
>
>
>
> Jesus
>
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