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Dear community,

I tried to process MS- patient's MRIs (mostly same scanner, same settings) 
Longitudinally over a long period of time. I first processed all timeponits 
crosssectionally and then initialised  the base image by recon- all - base TP1 
TP2 TP3 etc. Now I am trying to run label based morphometry and it seems some 
areas are growing rather than shrinking. Which is highly unlikely. I tried to 
exclude timepoint of a relapse to rule out perifocal edema interfering with 
measures but the problem remains.
Did anybody have the same problem?
Is it a potential bug or just a garbage in garbage out problem (though I don't 
know what would be wrong with our scans)?
Does it make sense to make an intermediate template for two timeponits only? 
I.e. recon- all -base TP1 TP2; recon -all -base TP2 TP3 ... and use them for 
longitudinal runs?

Thanks for your opinions. Best
Matthias
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