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Great.  Many thanks for your suggestions.
My best
Aj

On Wed, Jul 21, 2021, 12:31 Fischl, Bruce <bfis...@mgh.harvard.edu> wrote:

> There isn’t really anything available for the latter approach. I would
> suggest the former and potentially including site as a nuisance variable.
> You very much want to balance across site in terms of whatever effect you
> are looking for (e.g. don’t scan all your patients on one and all your
> controls on the other)
>
>
>
> Cheers
>
> Bruce
>
>
>
> *From:* freesurfer-boun...@nmr.mgh.harvard.edu <
> freesurfer-boun...@nmr.mgh.harvard.edu> *On Behalf Of *AJ
> *Sent:* Wednesday, July 21, 2021 1:15 PM
> *To:* Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
> *Subject:* Re: [Freesurfer] Intensity equalization
>
>
>
> *        External Email - Use Caution        *
>
> Thank you so much for your reply.
>
>
>
> I have subjects who got MRIs on either GE or PH.  There are mild image
> intensity differences between the two scanners.  To combine volumetric data
> from both scanners, an easier way would be to express volumes as percentage
> of sbTIV (a less variable measure than eTIV) from respective scanners using
> SAMSEG.  Or more involved process would be intensity normalization of scans
> to each other and then subsequent SAMSEG analysis.  I think the former
> approach is easier and still valid?  The later approach would require an
> additional program, if you would suggest one?
>
>
>
> Many thanks
>
>
>
> AJ
>
>
>
> On Wed, Jul 21, 2021, 09:40 Fischl, Bruce <bfis...@mgh.harvard.edu> wrote:
>
> Hi AJ
>
>
>
> No, not easily. Maybe you can tell us your overall goal to see if we can
> help?
>
>
>
> Cheers
> Bruce
>
>
>
> *From:* freesurfer-boun...@nmr.mgh.harvard.edu <
> freesurfer-boun...@nmr.mgh.harvard.edu> *On Behalf Of *AJ
> *Sent:* Wednesday, July 21, 2021 1:27 AM
> *To:* Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
> *Subject:* [Freesurfer] Intensity equalization
>
>
>
> *        External Email - Use Caution        *
>
> Hi,
>
> I have 2 MRIs on different scanners. The tissue contrasts are slightly off
> and there is slight differences in the volumes of ROIs. Is there a way to
> make both MRIs have the same intensity? I.e., Im2's intensity follows Im1's
> intensity?
>
> Many thanks
>
> AJ
>
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