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Hello Yiota,


the whole hippocampus value is a sum of all subregions except for the 
hippocampal fissure - best try to reproduce this in an example.


The recon-all pipeline also delivers a total hippocampal volume, but it is an 
entity/result of its own and produced independently of

the subfield segmentation. It indirectly also contains areas that in the 
subfield segmentation would go to the fissure.


There is several papers out that compared the two, generally the subfield based 
sum value is considered more reliable.


Best,

Philipp


________________________________
Von: freesurfer-boun...@nmr.mgh.harvard.edu 
<freesurfer-boun...@nmr.mgh.harvard.edu> im Auftrag von Panayiota Ventura 
<panayiota.vent...@gmail.com>
Gesendet: Montag, 21. Juni 2021 21:27
An: freesurfer@nmr.mgh.harvard.edu
Betreff: [Freesurfer] Hippocampal Subfields/ASEG


        External Email - Use Caution

Hello,

I have a couple of questions concerning the hippocampal subfield extractions as 
well as the hippocampus extraction included in ASEG. I have looked around and 
tried to find as much information as possible about the two but I can't seem to 
find a clear answer. I'm hoping someone can help me out with this.

1. In the hippocampal subfields extraction, one of the labels is called "whole 
hippocampus". I would like to know what exactly is meant by that? In other 
words, what hippocampal regions are included in this "whole hippocampus" label?

2. The ASEG atlas also includes a hippocampus extraction. However this value is 
different from that of the hippocampal subfield extraction. What hippocampal 
regions are being included in this hippocampal extraction.

3. Which of the two would be a better estimate of hippocampal volume?

Thank you for your time and help!

Kind regards,

Yiota Ventura

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