Hi Stephanie

I’m not sure you can really compare their accuracy. Thickness is easier to 
interpret though and is also a point measure and relatively insensitive to head 
size, so is frequently an easier surrogate biomarker than surface area. That 
said, we have done studies of surface area change

Cheers
Bruce

From: freesurfer-boun...@nmr.mgh.harvard.edu 
<freesurfer-boun...@nmr.mgh.harvard.edu> On Behalf Of Stephanie K
Sent: Monday, January 25, 2021 1:09 PM
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] Thickness vs surface area


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Hello,

I am performing analyses looking at brain measures for a neurodegenerative 
disorder. I wanted to ask whether the accuracy for surface area is as high as 
is for thickness? I would appreciate your advice or any references.

Thanks

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